Stimuli-responsive polymeric materials for human health applications  

作　　者：Molla R.Islam Yongfeng Gao Xue Li Qiang Matthew Zhang Menglian Wei Michael J.Serpe 

机构地区：[1]Department of Chemistry, University of Alberta, Edmonton, AB T6G 2G2, Canada

出　　处：《Chinese Science Bulletin》2014年第32期4237-4255,共19页

基　　金：Michael J.Serpe acknowledges funding from the University of Alberta(the Department of Chemistry and the Faculty of Science);the Natural Sciences and Engineering Research Council of Canada(NSERC);the Canada Foundation for Innovation(CFI);the Alberta Advanced Education&Technology Small Equipment Grants Program(AET/SEGP),IC-IMPACTS,and Grand Challenges Canada

摘　　要：Stimuli-responsive polymers have the extraordinary ability to change their physical and/or chemical state after they‘‘detect’’a change in their environment;their response depends dramatically on their chemical composition.This property has been used for a plethora of applications;this review highlights their utility for human health.Specifically,this review will highlight efforts in the areas of sensing and biosensing,antimicrobial/antifouling coatings,tissue engineering and regenerative medicine,and drug delivery.Specific examples are given in each of these areas,with some focus on our work engineering poly(Nisopropylacrylamide)-based microgels and other responsive systems.Stimuli-responsive polymers have the extraor- dinary ability to change their physical and/or chemical state after they ＂detect＂ a change in their environment; their response depends dramatically on their chemical compo- sition. This property has been used for a plethora of applications; this review highlights their utility for human health. Specifically, this review will highlight efforts in the areas of sensing and biosensing, antimicrobial/antifouling coatings, tissue engineering and regenerative medicine, and drug delivery. Specific examples are given in each of these areas, with some focus on our work engineering poly（N- isopropylacrylamide）-based microgels and other respon- sive systems.

关 键 词：聚合物材料 刺激响应性 人体健康 应用 N-异丙基丙烯酰胺 化学状态 生物传感 组织工程 

分 类 号：TQ317[化学工程—高聚物工业]