亚急性甲状腺炎患者炎性指标与FT3和FT4相关性分析  

Relationship between inflammatory markers levels and FT3, FT4 in subacute thyroiditis

作　　者：应长江[1] 周晓燕[2] 周冬梅[1] 凌宏威[1] 孙娟[1] 范静静[1] 李伟[1] 

机构地区：[1]徐州医学院附属医院内分泌科,江苏徐州221001 [2]徐州医学院形态实验室,江苏徐州221001

出　　处：《中国医药科学》2014年第19期170-172,216,共4页China Medicine And Pharmacy

摘　　要：目的观察亚急性甲状腺炎患者炎性指标与FT3和FT4相关性,探讨炎症指标在亚急性甲状腺炎诊断中的意义。方法回顾性分析我院诊断明确亚甲炎患者53例,患者甲状腺疼痛评分表由本小组制定,患者炎症指标、FT3(free triiodothyronine)、FT4(free thyroxine)在我院实验室检测。结果甲状腺疼痛评分与FT3、FT4、ESR(erythrocyte sedimentation rate)、CRP(C-reactive protein)和FIB(fibrinogen)均有正相关性,与ESR相关性最高。FT3与FT4、ESR、CRP具有正相关性(P<0.05),其中与FT4呈强正相关性。FT4与ESR和CRP具有相关性(P<0.05),与FIB无相关性;ESR与FT3、FT4、CRP、FIB有正相关性(P<0.05)。CRP与FT3、FT4、ESR、FIB具有正相关(P<0.05),FIB与ESR、CRP有相关性(P<0.05)。结论亚急性甲状腺炎炎症指标能够比较客观反映临床体征和病情严重程度,其中ESR对临床判断病情严重程度有较好的价值。Objective To observe correlation between inflammatory markers levels and FT3, FT4 in subacute thyroiditis, and evaluate the clinical significance of the inflammatory markers in diagnosing. Methods 53 patients with subacute thyroiditis were retrospectively analyzed. The thyroid gland pain score was made byresearcher; FT3, FT4, ESR, CRP and FIB were tested in laboratory. Results The thyroid gland pain score had positive correlation with FT3, FT4, ESR, CRP and FIB（P〈0.05）. FT3 had positive correlation with FT4, ESR and CRP（P〈0.05）. FT4 had positive correlation with ESR and CRP（P〈0.05）. ESR had positive correlation with FT4, FT3, CRP and FIB（P〈0.05）. CRP had positive correlation with FT3, FT4, ESR and FIB（P〈0.05）. FIB had positive correlation with ESR and CRP（P〈0.05）. Conclusion Inflammatory markers levels are able to reflect the clinical signs and the severity of the illness in subacute thyroiditis objectively. The ESR is good value for clinical judgment illness severity.

关 键 词：亚急性甲状腺炎 ESR CRP FIB FT3 FT4 

分 类 号：R581.4[医药卫生—内分泌]