计算机辅助设计与制造技术在个性化甲状软骨重建中的应用  

The application of CAD/CAM technology on the reconstruction of the thyroid cartilage

作　　者：张龙城[1] 胡万青[2] 黄海波[3] 夏薇[4] 曹高翔[4] 

机构地区：[1]中国人民解放军第三0三医院耳鼻咽喉头颈外科,南宁530021 [2]马鞍山市人民医院耳鼻咽喉科 [3]中国人民解放军第三0三医院放射科 [4]广西大学材料科学与工程学院

出　　处：《临床耳鼻咽喉头颈外科杂志》2014年第19期1487-1490,共4页Journal of Clinical Otorhinolaryngology Head And Neck Surgery

基　　金：全军医药卫生科研项目(面上项目No:06MA122);广西自然科学基金项目(No:2011GXNSFA018209)

摘　　要：目的:探讨计算机辅助设计/计算机辅助制造(CAD/CAM)技术在甲状软骨缺损的个性化修复重建中的价值。方法:选取30只成年新西兰大白兔(雌雄不限),随机分为2组。A组在术前行喉部CT扫描,三维重建甲状软骨成像,手术切除任意一侧甲状软骨,缺损处植入运用CAD/CAM技术和镜像技术制备的个性化修复材料;B组手术切除任意一侧甲状软骨,缺损处植入大致按照实验动物单侧甲状软骨制作的非个性化修复材料。术后通过大体观察、电子喉镜检查等观察实验动物的喉腔情况。结果:A组实验动物喉腔黏膜无炎症、无肉芽生长,声带闭合良好,喉腔通畅、无塌陷现象发生;B组喉腔黏膜无炎症,第3周喉前连合处见肉芽生长,第7周见术侧喉腔轻度塌陷,喉腔欠通畅,声带闭合欠佳。结论:运用CAD/CAM技术制备的个性化修复材料比非个性化材料能起到更好的喉支撑作用。CAD/CAM技术为术前设计提供了个性化实体模型,提高了手术的精确性,节省了手术时间,降低了手术并发症。Objective：To explore the value of computer-aided design/computeraided manufacturing（CAD/CAM）technology for individual reconstruction of the thyroid cartilage defects.Method：Select the 20 New Zealand white rabbits（male or female）.Randomly divided into two groups.Group A in the pre-operative CT scan of the throat,three-dimensional reconstruction of the thyroid cartilage imaging,surgical removal of either side of the thyroid cartilage,defect implanted in the use of CAD/CAM technology and mirror technology to produce personalized restorative materials;Group B surgical resection either side of the thyroid cartilage,defect implanted production of non-personalized probably according to the experimental animals unilateral thyroid cartilage repair materials.After surgery by gross observation,electronic laryngoscopy observed experimental animals throat.Result：General check and electronic laryngoscopy show：the use of CAD/CAM technology to prepare the individual repair materials throat plays better supporting role than the non personalized materials.Conclusion：CAD/CAM technology before surgery designed to provide a personalized solid model to improve the accuracy of the surgery,time saving surgery to reduce surgical complications.

关 键 词：CT扫描 计算机辅助设计/计算机辅助制造 甲状软骨 个性化重建 

分 类 号：R764[医药卫生—耳鼻咽喉科]