健康青年人气导短纯音诱发的眼肌前庭诱发肌源性电位  

Normal value of air-conducted ocular evoked myogenic potential in young people

作　　者：王佩杰[1,2] 罗伟 陆小燕 吴麟 陈震宇 王干 郝虹 赵武伟 

机构地区：[1]安徽医科大学解放军八一临床学院,南京210002 [2]解放军八一医院耳鼻咽喉头颈外科

出　　处：《临床耳鼻咽喉头颈外科杂志》2014年第19期1495-1498,共4页Journal of Clinical Otorhinolaryngology Head And Neck Surgery

基　　金：南京军区十二五科研基金课题资助(No:MS057)

摘　　要：目的:探讨健康青年人群气导短纯音诱发的眼肌前庭诱发肌源性电位(oVEMP)的特征性参数,并进行参数分析及正常值的计算。方法:55例健康青年人作为受试者,均采用500Hz气导短纯音单侧给声对侧记录。记录55例(110耳)的P1-N1复合波引出阈值,P1和N1的潜伏期,P1-N1波间期及P1-N1复合波振幅,以获得临床正常值范围,同时分析性别对oVEMP各参数的影响。结果:55例(110耳)均引出典型的P1-N1复合波,引出率为100%。oVEMP的引出阈值(正常听力级nHL)为(82.23±2.92)dBHL;95dBHL气导短纯音刺激下获得P1的潜伏期(11.53±0.80)ms;N1的潜伏期(16.61±0.87)ms,P1-N1波间期(5.18±1.04)ms,P1-N1复合波振幅(5.96±2.59)μV。31例男性受试者P1-N1复合波振幅为(6.49±2.67)μV,24例女性为(5.28±2.34)μV,二者比较差异有统计学意义(P<0.05)。结论:气导短纯音诱发的oVEMP是一种新兴的前庭功能检测方法,在oVEMP的P1-N1复合波振幅上存在性别差异,应按照性别分别建立oVEMP的正常值范围。Objective：To investigate the characteristics of air-conducted ocular vestibular-evoked myogenic potential（oVEMP）in healthy young people,so as to establish the normative data of young people.Method：Fiftyfive healthy young subjects were recruited as study participants,500 Hz air-conducted tone burst was used as stimulation.The threshold of oVEMP in each ear was examined.The latencies of P1 and N1,P1-N1 interval,peakto-peak of P1-N1 amplitude and asymmetry ratio were measured.Effects of gender on oVEMPs were also examined.Result：The typical complex wave of N1 and P1was observed in all subjects.The threshold of oVEMP examination was（82.23±2.92）dBHL,95 dBHL air-conducted get the latencies of P1 and N1,P1-N1 interval,peak-topeak P1-N1 amplitude in these healthy young people were（11.53±0.80）ms,（16.61±0.87）ms,（5.18±1.04）ms,（5.96±2.59）μv,respectively.The peak-to-peak P1-N1 amplitude of male was（6.49±2.67）μv,the female was（5.28±2.34）μv,there were significant differences between male and female subjects in the wave amplitude（P〈0.05）.Conclusion：Air-conduction induced oVEMP is a new method for vestibular function test.The amplitude of the oVEMP wave was different between male and female.Therefore it is necessary to establish the normal value according to genders.

关 键 词：眼肌前庭诱发肌源性电位 阈值 潜伏期 

分 类 号：R764.41[医药卫生—耳鼻咽喉科]