腰痛贴膏对家兔腰椎间盘突出症模型的影响  

The Influence of Osphyalgia Strapping on Prolapse Lumbar Intervertebral Disc Model in Rabbit

作　　者：杜佳林[1] 包玉龙[1] 李显石 范英兰[1] 甘雨[1] 乔菊久[1] 李淼[1] 李显华[1] 

机构地区：[1]辽宁省中医药研究院,沈阳110034 [2]沈阳市农业科学院,沈阳110034

出　　处：《实验动物科学》2014年第4期32-35,40,共5页Laboratory Animal Science

摘　　要：目的观察腰痛贴膏对家兔腰椎间盘突出症模型的影响。方法采用手术方法将圆形滤纸片放于家兔骶神经根腋窝部,造成家兔腰椎间盘突出症模型,观察腰痛贴膏对家兔腰椎间盘突出症模型的影响。结果腰痛贴膏各给药组兔的全瘫恢复、痛觉恢复、触觉恢复均比模型组提前,恢复比例比模型组高,以腰痛贴膏高剂量组恢复最好,从全瘫到半瘫,半瘫到恢复的阳性率均达90%以上;腰痛贴膏中、高剂量组滤纸片重量明显减小,血液流变学全血黏度明显降低、红细胞电泳时间明显缩短。结论腰痛贴膏能减轻神经干水肿、充血、变性及异物肉芽肿的形成,具有促进神经纤维恢复、神经干的传导和改善模型兔瘫痪下肢尽快恢复的作用;同时具有改善微循环、增加血流量和改善血液流变学的作用。Objective To observe the influence of osphyalgia strapping on rabbit prolapse lumbar intervertebral disc model. Method With the surgical method, the round filter paper was placed on axillary region of sacral nerve root. In order to observe the influence of osphyalgia strapping on rabbit prolapse lumbar intervertebral disc model.Result Paralysis recovery, pain recovery and touch recovery of medication administration groups were all ahead of time in comparison with model group, and the recovery ratio was higher. The recovery of high dose group was the best with the positive rate reaching more than 90% from complete paralysis to semiparalysis and from semiparalysis to recovery; in middle and low dose group, the filter paper weight decreased obviously, whole blood viscosity reduced sharply, and erythrocyte electrophoretic time shortened evidently. Conclusion Osphyalgia strapping had the role of lightening nerve-trunk edema, hyperemia, denaturation, foreign body grannuloma formation; promoting nerve fiber＇s recovery and nerve-trunk＇s conduction, improving lower limbs＇ paralysis; and osphyalgia strapping had the role of improving microcirculation and hemorheology with increasing the blood flow.

关 键 词：腰痛贴膏 家兔 腰椎间盘突出症模型 

分 类 号：Q95-33[生物学—动物学]