沙参麦冬汤加减联合化疗治疗中晚期非小细胞肺癌  

Modified Shashen Maidong Tang Combined with Chemotherapy Treatment in Treating Patients with Locally Advanced Non-small Cell Lung Cancer

作　　者：李新 刘茂军[2] 

机构地区：[1]天津市北辰区医院药剂科,天津300000 [2]天津市和平区中医医院,天津300000

出　　处：《中国实验方剂学杂志》2014年第20期195-198,共4页Chinese Journal of Experimental Traditional Medical Formulae

摘　　要：目的:探讨和分析对中晚期非小细胞肺癌患者采取加减沙参麦冬汤联合化疗治疗的临床疗效及价值。方法:选取中晚期非小细胞肺癌患者68例,随机分成对照组和研究组,对照组采用常规化疗,研究组在对照组治疗的基础上联合给予加减沙参麦冬汤治疗,对比两组患者在生活质量改善、病灶稳定情况及治疗效果等指标的差异性。结果:两组患者治疗前生活质量评分对比无明显差异,但治疗后两组间生活质量评分对比差异有统计学意义,且研究组病灶稳定率及总治疗有效率均明显高于对照组(P<0.05)。结论:临床上对中晚期非小细胞肺癌患者应用化疗联合加减沙参麦冬汤治疗,疗效显著,且利于稳定病灶,这对改善患者生存质量,延长存活时间有着积极的意义,有一定的临床推广价值。Objective：To investigate and analysis the clinical curative effect and the clinical value of modified Shashen Maidong tang combined with chemotherapy treatment for patients with locally advanced non-small cell lung cancer （NSCLC）.Method：Sixty-eight patients were enrolled and randomly divided into control group and observation group.Patients in both group received conventional chemotherapy treatment,and patients in observation added modified Shashen Maidong tang.The improvementin quality of life,stablility of lesions and indexes of therapeutic effectwere compared between two groups.Result：Therewas no significant differencein quality of lifescore between the two groups before the treatment.While the quality of life score,the stability rate of lesions and the total curative rate showed significant improvement after the treatment,and observation group was superior to control group （P ＜ 0.05）.Conclusion：Clinical application of Shashen Maidong tang combined chemotherapy treatment has remarkable curative effect in patients with NSCLC in terms of improving the survival and quality of life,and this method has certain clinical value.

关 键 词：中晚期非小细胞肺癌 沙参麦冬汤 化疗 临床疗效分析 

分 类 号：R287.6[医药卫生—中药学]