丹莪妇康煎膏对子宫内膜异位症大鼠血清IL-6和IL-8含量的影响  

Effects of Danefukang Jiangao on the Expression of IL-6 and IL-8 in Endometriotic Rats

作　　者：沈龙德[1] 李爱禄[1] 尤嘉萍[1] 贺锦曦[1] 李纯孝[1] 

机构地区：[1]福建医科大学附属泉州第一医院妇产科,福建泉州362000

出　　处：《中国伤残医学》2014年第21期14-15,共2页Chinese Journal of Trauma and Disability Medicine

摘　　要：目的：探讨丹莪妇康煎膏对子宫内膜异位症（ EMS）大鼠血清中IL-6和IL-8含量的影响及治疗EMS的机制。方法：建立大鼠EMS模型，SD大鼠随机分为空白组、模型组和治疗组，每组10只，采用ELISA法检测各组大鼠血清中IL-6和IL-8含量。结果：与模型组相比，治疗组大鼠血清中IL-6和IL-8含量明显下调。结论：降低血清中IL-6和IL-8含量可能是丹莪妇康煎膏治疗子宫内膜异位症的机制之一。Objective：To investigate the effects of Danefukang jiangao on the expression of IL-6 and IL-8 of endometriotic rats. Methods：Rats were randomly divided into 3 groups：control group,model group and test group.The expression of IL-6 and IL-8 were detected by ELISA.Results：Compared with model group,the expression of IL-6 and IL-8 were decreased significantly in test group. Conclusion：The Danefukang jiangao can treat the endometriosis in rats,and its action may be associated with decreasing the expressions of IL-6 and IL-8 in ectopic endometrium.

关 键 词：丹莪妇康煎膏 子宫内膜异位症 IL-6 IL-8 

分 类 号：R711.71[医药卫生—妇产科学]