中风康复运动中脑电-肌电相干性分析  

Analysis of Corticomuscular Coherence during Rehabilitation Exercises after Stroke

作　　者：马培培[1] 陈迎亚[1] 杜义浩[1] 苏玉萍 吴晓光[1] 梁振虎[1] 谢平[1] 

机构地区：[1]燕山大学电气工程学院,秦皇岛066004 [2]秦皇岛人民医院康复科,秦皇岛066000

出　　处：《生物医学工程学杂志》2014年第5期971-977,共7页Journal of Biomedical Engineering

基　　金：国家自然科学基金资助项目(61271142;61102005);秦皇岛市科学技术研究与发展计划项目资助(201302A218;2012021A040)

摘　　要：本文针对中风康复患者运动功能障碍相关的神经肌肉功能评价问题,研究有效的脑电(EEG)信号与肌电(EMG)信号相干性分析及相干显著性判断方法,探索运动功能障碍患者的脑、肌电相干差异性表现。提出一种基于小波分解的脑、肌电相干性分析方法,定义了相干显著性指标定量描述EEG、EMG信号在某频域内的相似性和锁相活动。通过对中风患者和健康人膝关节"屈"、"伸"运动中脑、肌电相干性分析实验,得到以下结论:在相同运动模式下患者健侧的脑、肌电相干性与正常人无明显差异,患者患侧的脑、肌电相干性在gamma频段存在明显缺失;但随着运动功能的康复,患者患侧的脑、肌电相干性与健侧gamma频带脑、肌电相干性的差异会逐渐减小。To better evaluate neuromuscular function of patients with stroke related motor dysfunction, we proposed an effective corticomuscular coherence analysis and coherent significant judgment method. Firstly, the related func- tional frequency bands in the electroencephalogram （EEG） were extracted via wavelet decomposition. Secondly, co herence were analysed between surface electromyography （sEMG） and sub-bands extracted from EEG. Further more, a coherent significant indicator was defined to quantitatively describe the similarity in certain frequency domain and phase lock activity between EEG and sEMG. Through the analysis of corticomuscular coherence during knee flexion-extension of stroke patients and healthy controls, we found that the stroke patients exhibited significantly lower gamma-band corticomuscular coherence in performing the task with their affected leg, and there was no statis- tically significant difference between their unaffected lag and the healthy controls, but with the rehabilitation train ing, the bilateral difference of corticomuscular coherence in patients decreased gradually.

关 键 词：康复评价 脑电 肌电 小波时频分解 脑、肌电相干性 

分 类 号：R49[医药卫生—康复医学]