复方熊果苷乳膏治疗48例老年黄褐斑疗效观察  

Clinical efficacy of compound arbutin cream in the treatment of patients with chloasma

作　　者：白桦[1] 刘法[2] 

机构地区：[1]解放军第253医院保健科,内蒙古呼和浩特010051 [2]呼和浩特市第一医院妇产科

出　　处：《中国美容医学》2014年第18期1545-1548,共4页Chinese Journal of Aesthetic Medicine

基　　金：内蒙古自治区自然科学基金(编号:2010MS1142)

摘　　要：目的:探讨复方熊果苷乳膏应用于老年黄褐斑的药理学作用。方法:将48例老年黄褐斑患者纳入研究,随机分为两组。观察组:24例,复方熊果苷乳膏+白芷祛斑膏治疗;对照组:24例,白芷祛斑膏治疗,观察疗效并比较两组的皮损面积、皮肤颜色、斑点和棕色斑绝对值的变化情况。结果:观察组总有效率87.50%,明显高于对照组62.50%,疗效比较有显著性差异(P<0.05);观察组治疗后的皮损面积、皮肤颜色积分明显低于对照组(P<0.05);观察组治疗后的VISIA皮肤测试斑点绝对分值、棕色斑绝对分值明显低于对照组(P<0.05)。结论:复方熊果苷乳膏的美白祛斑药理作用良好,临床治疗老年黄褐斑的疗效显著。Objective To investigate treatment of elderly patients with the pharmacological effects of compound arbutin cream in the chloasma. Methods The 28 cases ofchloasma were randomly divided into two groups,observation group （n=24）and controlgroup （n=24）,compound arbutin cream and angelica freckle cream were used to treat in the observation group, angelica freckle cream was used to treat in the control group. The clinical efficacy,the changes of lesion area, skin color, spots and brown spots in 2 groups were observed and compared. Results The total efficiency rate was 87.50% in the observation group,the total efficiency rate was 62.50% in the control group, theobservation group was significantly higher than the control group （P〈0.05）;the lesion area points ,skin color points in the observation group were significantly lower than the control group （P〈0.05）;the spot absolute value, brown spots absolute value in the observation group were significantly lower than the control group （P〈0.05）. Conclusion The whitening and freckle pharmacological effects of compound arbutin cream is good, the clinical treatment of senile melasma effect is remarkable.

关 键 词：黄褐斑 复方熊果苷乳膏 疗效观察 

分 类 号：R758.42[医药卫生—皮肤病学与性病学]