埃博拉病毒,何去何从  

Ebola virus,o je vais

作　　者：盛子洋[1] 范东瀛[1] 安静[1] 

机构地区：[1]首都医科大学基础医学院微生物学教研室,北京100069

出　　处：《微生物学免疫学进展》2014年第5期60-64,共5页Progress In Microbiology and Immunology

摘　　要：埃博拉病毒(Ebola Virus,EBOV)是丝状病毒科的单股负链RNA病毒,其形态呈丝状,共有5个型别,其中扎伊尔型致死率高,曾在非洲大陆引起多次暴发。EBOV自然宿主尚不明确,猪、非人灵长类及蝙蝠都可能与病毒的传播有关,其中果蝠的关系最为密切。由于EBOV的毒力强和传播性强,加之目前尚无特效药物和疫苗,被列为生物危害四级,同时也被视为生物恐怖主义的工具之一。最近该病毒在西非肆虐人类,引起了广泛关注,因而就此做一综述,供广大同行参考。The Ebola Virus （ EBOV） is a single strand negative RNA virus , which belongs to Filoviridae.The virus shows a filamentous shape.There are five serotypes.Of those, Zaire EBOV is most fatality and has caused outbreaks in Africa . The natural hosts and transmission routes for EBOV are unclear , and the pig , non-human primates and bats , particularlly fruit bat may be associated with the virus spreading .Because of the high virulence and strong infectivity , and there is no ef-fective drugs and licensed vaccine currently available , EBOV are classified as biosafety level 4.Recently the virus caused outbreak in west Africa and become an impact threat for hunan beings and caused the public concern .Therefore this review will focus on recent progress of EBOV research .

关 键 词：埃博拉病毒 病毒性出血热 自然宿主 ZMapp 丝状病毒 

分 类 号：R373.9[医药卫生—病原生物学]