艾滋病病毒感染者生命质量相关因素的通径分析  

A path analysis on related factors of quality of life in people with HIV/AIDS

作　　者：邱阳阳[1] 罗丹[1] 陈曦[2] 肖易[3] 厉洁 程睿[1] 

机构地区：[1]中南大学公共卫生学院社会医学与卫生事业管理系,长沙410078 [2]湖南省疾病预防控制中心,长沙410005 [3]中南大学湘雅医院皮肤性病科,长沙410083 [4]长沙市芙蓉区疾病预防控制中心,长沙410001

出　　处：《中国心理卫生杂志》2014年第10期729-734,共6页Chinese Mental Health Journal

基　　金：国家自然科学基金(81202290);湖南省社会科学基金(13WTB22)

摘　　要：目的:了解艾滋病病毒感染者/艾滋病患者(PLWH)的生命质量状况及其相关因素,为更好地开展临床治疗及关怀支持、提高PLWH的生命质量提供参考依据。方法:以系列取样方式,在某省会城市艾滋病综合防治信息系统确认登记的PLWH中选取370例,用艾滋病患者生命质量量表(MOSHⅣ)、病人健康问卷抑郁量表(PHQ-9)、广泛性焦虑量表(GAD-7)、社会支持评定量表(SSRS)及艾滋病压力量表(SS-HⅣ)进行调查,并运用结构方程模型分析各相关因素对生命质量的路径及效应。结果:本样本MOS-HⅣ总分为(55.6±21.0)分。通径分析结果显示,抑郁(β=-0.37)、焦虑(β=-0.01)对生命质量有直接负向预测作用,艾滋病相关压力除了对生命质量有直接负向预测作用(β=-0.39)外,还通过抑郁和焦虑间接预测生命质量(β=-0.25)。社会支持除了对生命质量有直接正向预测作用(β=0.08)外,还可通过艾滋病相关压力和抑郁间接预测生命质量(β=0.24)。结论:被调查的新确认PLWH人群总体生命质量水平较低;艾滋病相关压力、抑郁焦虑情绪、社会支持不足是其相关因素。Objective： To assess the quality of life in people with HIV/AIDS（PLWH） and its related factors, and to provide evidence for better clinical treatment, care and support for PLWH. Methods： Totally 370 PLWH newly identified by the HIV/AIDS prevention and control information system of a provincial capital in central part of China were consecutively selected. The Medical Outcomes Study HIV Health Survey （ MOS-HIV）, Patient Health Questionnaire Depression Module （PHQ-9）, Generalized Anxiety Disorder Scale （GAD-7）, Social Support Rating Scale （SSRS） and HIV/AIDS Stress Scale（SS-HIV） were administrated to participants, and structural equation modeling was used to analyze the influencing path and effect of related factors on quality of life. Results： The mean score of quality of life was （55.6 ±21.0）. Path analysis showed that depression （β = -0. 37） and anxiety （β= - 0. 01） had direct negative prediction effects on quality of life, and AIDS-related stress β = -0. 39） was directlynegatively related to quality of life and also indirectly related to the quality of life through depression and anxiety （β = -0. 25）. Social support was directly positively related to quality of life （β= 0. 08）, and also indirectly related to quality of life through depression and AIDS-related stress （β =0. 24）. Conclusion： The quality of life in newly iden- tified PLWH is poorer, and the HIV/AIDS related stress, depression and anxiety, low social support may be its re- lated factors.

关 键 词：艾滋病病毒感染者/艾滋病患者 生命质量 通径分析 现况调查 

分 类 号：R512.91[医药卫生—内科学]