桑寄生中槲皮素的提取工艺  

Optimized extraction conditions for quercetin of Taxilli Herba

作　　者：苏本伟[1,2,3] 张协君 朱开昕 赵明惠 李永华[3] 

机构地区：[1]钦州市中医药研究所,广西钦州535000 [2]钦州市中医医院,广西钦州535000 [3]广西中医药大学药学院,广西南宁530001

出　　处：《中国医院药学杂志》2014年第19期1638-1641,共4页Chinese Journal of Hospital Pharmacy

基　　金：国家自然科学基金面上项目(编号:81173537);广西中医药科技专项项目(编号:GZBZ14-21);广西自然科学基金项目(编号:2010GXNSFA013264)

摘　　要：目的:优选桑寄生中槲皮素的提取工艺。方法:采用正交试验方法,以槲皮素含量为考察指标进行试验。结果:优选的提取工艺条件为取桑寄生药材粉末加50倍量甲醇-盐酸(23∶2)溶液回流提取1次,每次2 h。结论:优选的提取方法操作简单、方便,工艺稳定可行,提取率较高,可作为桑寄生生产工艺及质量控制的参考。OBJECtIVE To optimize the extract process of quercetin from Taxilli Herba. METHODS The optimal technology of extraction was obtained by carrying out orthogonal experiment. RESULTS The best technical condition was as follows： the extraction was lasted for 2 h with methanol-hydrochliric acid（23 ： 2）, and the ratio of solid to solution was 1 ： 50. CONCLU- SION The method is simple, convenient, the process is stable and feasible, with high extraction rate, can be used as produc- tion engineering of Taxilli Herba and as the reference to the quality control.

关 键 词：桑寄生 槲皮素 提取工艺 正交试验 

分 类 号：R943[医药卫生—药剂学]