骨碎补复方制剂对股骨头坏死患者骨密度影响的研究  

Study on effects of rhizoma drynariae compound preparation on bone mineral density of patients with osteonecrosis of femoral head

作　　者：蒋家望[1] 李立新[1] 金源[1] 普蔼君[2] 普英[2] 

机构地区：[1]成都军区昆明疗养院,昆明650307 [2]成都军区昆明总医院

出　　处：《西南国防医药》2014年第10期1110-1111,共2页Medical Journal of National Defending Forces in Southwest China

摘　　要：目的观察中药骨碎补复方制剂对股骨头缺血性坏死患者骨密度的影响。方法 64例股骨头缺血性坏死患者采用3∶1分配比例,采用随机双盲、安慰剂平行对照方法分为治疗组和对照组,治疗组48例,口服中药骨碎补复方制剂;对照组16例,口服安慰剂,共服用24 w。在治疗前后分别用双能X线骨密度检测仪测量患者的腰椎、左髋、右髋骨密度。结果治疗24 w后,治疗组腰椎、左髋、右髋骨密度均较治疗前显著增加(P<0.05),而对照组无显著变化(P>0.05);治疗后治疗组与对照组比较,腰椎、左髋、右髋骨密度有显著增加(P<0.05)。结论中药骨碎补复方制剂治疗股骨头缺血性坏死的同时,对患者骨密度有明显的改善作用。Objective To observe the effects of rhizoma drynariae compound preparation on bone mineral density（BMD）of patients with avascular necrosis of femoral head.Methods Total 64 patients with avascular necrosis of femoral head were selected and divided into two groups in a proportion of 3∶1,i.e.the treatment group and control group,by means of randomly double-blind and placebo-control parallel study.The treatment group has 48 patients and took orally the traditional Chinese medicine-rhizoma drynariae compound preparation;the control group has 16 patients and took orally the placebo.Both groups were treated for 24 weeks in total.Before and after the treatment,dual-energy X-ray bone density detector was adopted for measuring the BMD at lumbar spine,and left and right hips of the patients.Results After 24 weeks＇ treatment,the BMDs at lumbar spine,and left and right hips of the patients in the treatment group significantly increased（P〈0.05）,while the patients in the control group had no significant change（P〈0.05）.Between the two groups after the treatment,the BMDs at lumbar spine,and left and right hips of the treatment group were significantly higher（P〈0.05）.Conclusion Rhizoma drynariae compound preparation can treat avascular necrosis of femoral head and obviously improve the BMD of the patients.

关 键 词：股骨头 缺血 坏死 骨碎补复方制剂 骨密度 

分 类 号：R687.3[医药卫生—骨科学]