子宫腺肌病患者血清CA125测定的临床价值  

Detection of serum CA125 in patients with adenomyosis and its significance

作　　者：杨舫[1] 金哲[2] 赵红[1] 

机构地区：[1]中日友好医院中医妇科,北京100029 [2]北京中医药大学东方医院妇科,北京100078

出　　处：《中日友好医院学报》2014年第5期267-269,共3页Journal of China-Japan Friendship Hospital

摘　　要：目的:探讨血清CA125水平对子宫腺肌病的诊断价值及其与痛经VAS评分、痛经时间长短、患者子宫大小的相关性。方法:选取我科门诊子宫腺肌病患者90例,健康体检人群68例,用化学发光免疫法检测2组血清CA125水平并比较分析。结果:子宫腺肌病患者血清CA125水平为89.01±70.87U/ml,阳性率78.89%,显著高于健康人群血清CA125水平(14.63±7.13U/ml,P<0.05)。CA125诊断子宫腺肌病的灵敏度为78.89%,特异度为98.53%。子宫腺肌病患者CA125水平与痛经VAS评分、痛经时间长短及子宫大小均无相关性(均P>0.05)。结论:血清CA125可作为子宫腺肌病的诊断指标之一;其与子宫腺肌病痛经程度及子宫大小无明显相关性。Objective：To investigate the diagnostic value of serum tumor markers carbohydrate antigen （CA125）in patients with adenomyosis.Methods：A total of 90 patients with adenomyosis and 68 healthy subjects were chosen.Serum CA125 in 2 groups was determined by chemical luminescence immunoassay method.Results：The positive rate of serum CA125 in patients with adenomyosis was 78.89％.And the level of CA125 in adenomyosis was significantly higher than that in normal subjects（89.01±70.87 vs 14.63±7.13,P＜0.05）,with 78.89％ sensitivity and 98.53％ specificity.Conclusion：CA125 may be a better marker for clinical diagnosis of adenomyosis.But there is no correlation between the level of serum CA125 and the severity of adenomyosis.

关 键 词：子宫腺肌病 血清CA125 痛经 

分 类 号：R711.71[医药卫生—妇产科学]