63株嗜麦芽寡养单胞菌的临床分布与耐药性分析  

Clinical distribution and drug resistance analysis for 63 isolates of Stenotrophomonas maltophilia

作　　者：徐飞[1] 刘雪梅[1] 迟富丽[1] 谈华[1] 常勇[1] 曹波[1] 

机构地区：[1]南京医科大学附属南京儿童医院检验科,江苏南京210008

出　　处：《检验医学》2014年第11期1141-1143,共3页Laboratory Medicine

摘　　要：目的了解嗜麦芽寡养单胞菌的临床分布及对抗菌药物的耐药性。方法采用VITEK-2 COMPACT全自动微生物鉴定仪及纸片扩散(K-B)法对分离的63株嗜麦芽寡养单胞菌的来源分布、药物敏感性结果进行统计分析。结果 63株嗜麦芽寡养单胞菌在临床标本中分布以痰液为主,占87.3%;感染主要发生在新生儿科为17.4%和胸外科17.4%;其次为呼吸科14.3%和重症监护病房(ICU)14.3%;嗜麦芽寡养单胞菌对亚胺培南耐药率为100.0%;而对左氧氟沙星、米诺环素、磺胺甲口恶唑-甲氧苄啶耐药率较低分别为1.6%、3.2%、3.2%。结论应加强对嗜麦芽寡养单胞菌耐药性监测,以指导临床根据药物敏感性试验结果合理选择抗菌药物。Objective To investigate the clinical distribution and drug resistance of Stenotrophomonas maltophilia. Methods The clinical distribution and drug resistance analysis for 63 isolates of Stenotrophomonas maltophilia were performed by VITEK-2 COMPACT system and Kirby-Bauer （K-B）method.The results were analyzed statistically. Results The isolation rate was the highest in respiratory specimens .There was a highest isolation rate of 87.3%.The samples were mainly obtained from the wards of Neonatology Department （1 7.4%）and Thoracic Surgery（1 7.4%）, followed by Respiratory Department （4.3%） and Intensive Care Unit （ICU ） （1 4.3%）.The 63 isolates of Stenotrophomonas maltophilia were highly resistant to imipenem,and the resistance rate was 1 00.0%.The resistance rates to levofloxacin,minocyline and triethoprim-sulfamethoxazole were 1 .6%,3.2% and 3.2%.Conclusions It should enhance drug resistance monitoring of Stenotrophomonas maltophilia.Treatment based on drug susceptibility test should be adapted as soon as possible.

关 键 词：嗜麦芽寡养单胞菌 耐药性 抗菌药物 

分 类 号：R378[医药卫生—病原生物学]