血锌、铁与血常规检测在儿童感染和贫血时的变化  

The changes of Zn,Fe and blood routine test in children with infection and anemia

作　　者：蔡眉[1] 唐振华[1] 余文[1] 

机构地区：[1]上海交通大学医学院附属中国福利会国际和平妇幼保健院,上海200030

出　　处：《检验医学》2014年第11期1164-1168,共5页Laboratory Medicine

摘　　要：目的：探讨儿童感染、贫血与微量元素锌（Zn）、铁（Fe）及血常规之间的关系。帮助临床更为合理的检查及补充微量元素。方法选取本院儿保门诊进行常规体检和就诊的1289例1～5岁儿童，感染组287例，贫血组303例，健康对照组699名。取末梢血进行微量元素和血常规检测。结果感染组末梢血 Zn（63．8±5．6）μmol／L 低于健康对照组 Zn（69．6±6．3）μmol／L，差异有统计学意义（P ＜0．05），末梢血 Fe（7．74±0．26） mmol／L 与健康对照组差异无统计学意义（P ＞0．05），白细胞（WBC）总数（10．9±2．4）×10^9／L 高于健康对照组（7．6±1．4）×10^9／L、中性粒细胞比例5％NEUT（37．9±14．5）％高于健康对照组（29．4±9．2）％，差异均有显著统计学意义（P ＜0．01）；贫血组末梢血 Fe（7．68±0．23）mmol／L 低于健康对照组 Fe（7．80±0．26）mmol／L，差异有显著统计学意义（P ＜0．01），末梢血 Zn（65．1±6．3）μmol／L 与健康对照组相比差异无统计学意义（P ＞0．05），血红蛋白（Hb）（110．5±6．8）g／L 低于健康对照组 Hb（127．4±5．6）g／L，差异有统计学意义（P ＜0．05），红细胞计数（RBC）、平均 RBC 体积（MCV）、平均 RBC Hb（MCH）、平均 RBC Hb 浓度（MCHC）均低于健康对照组，差异有显著统计学意义（P ＜0．01）；同时贫血组 Fe 含量低于感染组，差异有统计学意义（P ＜0．05）。结论感染和贫血患儿末梢血微量元素变化明显，尤其 Zn、Fe 指标的变化与血常规之间具有相关性。Objective To investigate the relationship of trace element zinc （Zn）,iron （Fe）and blood routine test with infection and anemia in children in order to determine and perform trace element supplementary reasonably. Methods A total of 1 289 children aged 1 to 5 years were enrolled.The 287 children with infection were selected as infection group,and 303 children with anemia were selected as anemia group.The 699 healthy children were selected as control group.The peripheral blood levels of trace elements and blood routine test were determined.Results The level of peripheral blood Zn in infection group [（63.8 ＆#177;5.6）μmol/L]was lower than that in control group [（69.6 ＆#177; 6.3）μmol/L]with statistical significance （P ＆lt;0.05）.The level of peripheral blood Fe in infection group [（7.74 ＆#177; 0.26）mmol/L]had no statistical significance with that in control group （P ＆gt;0.05）.The levels of white blood cell （WBC）[（1 0.9 ＆#177;2.4）＆#215;1 09 /L]and 5% neutrophilic granulocyte （NEUT）[（37.9 ＆#177;1 4.5）%]in infection group were higher than those in control group [WBC（7.6 ＆#177;1 .4）＆#215;1 09 /L and 5%NEUT（29.4 ＆#177;9.2）% ,P ＆lt;0.01 ].The level of peripheral blood Fe in anemia group [（7.68 ＆#177;0.23）mmol/L]was lower than that in control group [（7.80 ＆#177; 0.26）mmol/L]with statistical significance （P ＆lt;0.01 ）,and the level of peripheral blood Zn in anemia group [（65.1 ＆#177;6.3）μmol/L]had no statistical significance with that in control group （P ＆gt;0.05）.Hemoglobin （Hb）in anemia group[（1 1 0.5 ＆#177;6.8）g/L]was lower than that in control group [（1 27.4 ＆#177;5.6）g/L,P ＆lt;0.05].The contents of red blood cell （RBC）,erythrocyte mean corpuscular volume （MCV）,mean corpuscular hemoglobin （MCH）and mean corpusular hemoglobin concentration （MCHC）in anemia group were lower than those in control group with statistical significance （P ＆lt;0.01 ）.The level of Fe in anemia group was

关 键 词：锌 铁 感染 贫血 变化 

分 类 号：R446.11[医药卫生—诊断学]