两种基因型的MRSA感染的危险因素分析  

Analysis of risk factors of two genotypes of MRSA infection

作　　者：张玫娜[1] 曹杨[1] 曹忠帅[1] 

机构地区：[1]吉林大学第一医院二部检验科,吉林长春130031

出　　处：《中国实验诊断学》2014年第10期1660-1661,共2页Chinese Journal of Laboratory Diagnosis

摘　　要：目的通过研究本地区SCCmecⅡ及Ⅲ型耐甲氧西林金黄色葡萄球菌(MRSA)感染的相关危险因素,进而为治疗和预防不同基因型的MRSA感染提供依据。方法采用病例对照研究,对SCCmecⅡ及SCCmecⅢ型MRSA感染的相关危险因素进行统计分析。结果 SCCmecⅡ、SCCmecⅢ型MRSA感染与是否入住ICU有明显统计学差异(P<0.05)。而性别、年龄、住院时间、手术史、住院史、侵袭性操作、恶性肿瘤、严重皮肤损伤及预后情况在SCCmecⅡ和SCCmecⅢ型MRSA间并无明显的统计学差异(P>0.05)。结论相比较与SCCmecⅢMRSA而言,入住ICU的患者更容易感染SCCmecⅡMRSA。而性别、预后、年龄、住院时间、手术史、住院史、侵袭性操作、糖尿病、严重皮肤损伤、恶性肿瘤、抗生素种类对于SCCmecⅡ、SCCmecⅢ型MRSA并无明显统计学差异。Objective By studying risk factors of MRSA infection between SCCmec Ⅱ and SCCmec Ⅲ type in this region,then provide basis for the prevention and treatment of different MRSA genotypes infection.Methods SCCmecⅡ and SCCmec Ⅲ type of MRSA infection associated risk factors were analyzed with the case-control study.Results The risk factor of ICU stay was significant difference between SCCmec Ⅱ,SCCmec Ⅲ type of MRSA （P〈0.05）. However,no statistical significant difference in other risk factors such as gender,age,durati hospitalization time,history of surgery,hospitalization history,invasive operation,malignant tumor,severe skin lesions and prognosis between SCC-mec Ⅱ and SCCmecⅢ type of MRSA （P〉0.05）.Conclusion Compared with the SCCmecⅢ MRSA the patients ad-mitted ICU were more susceptible to SCCmec Ⅱ MRSA.However,gender,prognosis,age,hospitalization time,history of surgery hospitalization history,invasive operation,diabetes,severe skin lesions,malignant tumor and antibiotics for SCCmec Ⅱ,SCCmec Ⅲ type MRSA did not differ significantly.

关 键 词：耐甲氧西林金黄色葡萄球菌 危险因素 

分 类 号：R515[医药卫生—内科学]