兰州市城镇多体检中心人群血脂异常流行病学特点及危险因素分析  

The epidemiology and risk factor of dyslipidemia for people in multiple physical examination center in Lanzhou

作　　者：周珊珊[1] 张永霞 陈玉霞 袁帆 王志剑 武美丽[6] 何津祥[7] 何津春[8] 

机构地区：[1]兰州大学第一临床医学院,甘肃兰州730000 [2]玉门市第一人民医院检验科,甘肃玉门735211 [3]兰州市城关区医院检验科,甘肃兰州730000 [4]兰州市安宁区疾病控制中心,甘肃兰州730000 [5]河源市源城区人民医院检验科,甘肃河源517000 [6]甘肃省妇幼保健院生殖内分泌科,甘肃兰州730000 [7]兰州大学第一医院放疗科,甘肃兰州730000 [8]兰州大学第一医院医学检验中心,甘肃兰州730000

出　　处：《国际检验医学杂志》2014年第18期2471-2473,2475,共4页International Journal of Laboratory Medicine

基　　金：国家"十五"重大科技专项资助项目(2002DA711A028-17);教育部科技基础平台建设资助项目(505015);甘肃省自然科学研究基金资助项目(1308RJZA218);横向课题基金资助项目(2012620111000212)

摘　　要：目的了解兰州市城镇体检人群血脂异常流行病学特点及血脂异常的危险因素，为血脂异常的防治工作提供依据。方法采用分层整群随机抽样抽取兰州市5家医院体检人群共4505例，进行问卷调查、体格检查和实验室检测。结果该人群血脂异常的总患病率为45．79％，以高三酰甘油（TG）为主；血清总胆固醇（TC）、TG、高密度脂蛋白胆固醇（HDL—C）、低密度脂蛋白胆固醇（LDL-C）的总体水平分别为（5．27±1．08）、（1．74±1．38）、（1．41±0．43）、（2．83±0．82）mmol／L；男性血脂异常率为53．49％，女性为34．93％，男性以35～〈45岁检出率最高，女性以55～〈65岁检出率最高；两性低龄组的HDL-C均呈现较低水平；心血管危险因素在血脂异常患者中有聚集现象。非条件Logistic回归分析显示，年龄（OR=1.701）、超重肥胖（OR=5．560）、腹部肥胖（OR=2．398）、吸烟（OR=0．545）、喜食油腻（OR=5．313）、睡眠质量差（OR=2．005）、舒张压（OR=3．061）是血脂异常的危险因素。结论兰州市城镇体检人群血脂异常问题严峻，应采取控制体质量、合理膳食、改善睡眠、控制血压等关键性措施。Objective To explore the status and risk factors of the dyslipidemia among health examination population of Lanzhou for providing the intervention measures. Methods According to the stratified cluster random sampling method,4 505 health examination individuals were recruited for the study from 5 hospitals in the Lanzhou region through questionnaire,biochemical analysis. Results Prevalence of dyslipidemia of the population was 45.79 %,high TG was the main type. The level of serum TC,TG, HDL-C and LDI.-C were （5.27±1.08） ,（1.74±1.38） ,（1.41±0.43） and （2.83±0.82）mmol/L. The prevalence was 53.49% in male, and 34. 93% in female. The prevalence was higher among the group of 35-〈45 years old for male and 55-〈65 years old for fe male. The level of HDL-C was low among young people. There was aggregation of risk factors among the participants with dyslipidemia. Non-conditional logistic regression analysis showed that the risk factors were age（OR= 1. 701 ）, overweight（OR=5. 560）, abdominal obesity（OR=2. 398） ,smoking（OR =0. 545） ,intake of greasy diet（OR=5. 313） ,sleep quality（OR=2. 005） and diastolic blood pressure（OR=3. 061）. Conclusion Lipid disorders becomes a serious problem in the health examination population,measures such as rational diet, weight control, sleep improvement, pressure control and quiting smoking must be taken.

关 键 词：血脂异常 患病率 流行病学 危险因素 

分 类 号：R589.2[医药卫生—内分泌]