西宁地区无偿献血者抗-HIV检测结果分析  

Anti HIV test and results analysis of unpaid blood donors in Xining area

作　　者：李向国[1] 

机构地区：[1]青海省血液中心,青海西宁810000

出　　处：《国际检验医学杂志》2014年第18期2492-2493,2509,共3页International Journal of Laboratory Medicine

摘　　要：目的对青海西宁地区2008-2013年无偿献血者抗HIV检测结果分析，改进献血招募采集工作，杜绝经输血传播HIV的发生，保证临床输血安全。方法抗HIV检测采用ELISA方法，初筛阳性采用免疫印迹法（WB）进行确认。对检测结果进行统计并分析。结果共检测无偿献血者标本201652例次，WB确认HIV感染者54例，阳性率为0．027％，感染者中以男性为主，占90．7％，以21～〈41岁年龄段为高发年龄段，占68．5％。ELISA试验S／CO值与确证试验的阳性符合率威正比，单种ELISA试剂和2种ELISA试剂检测阳性结果与确证结果阳性符合率分别为0％和87％，54例感染者都为抗HIVl型，抗HIV的特异带gp160、gp120、P24、P17均lOO％出现。结论献血者中HIV感染整体处于低流行平稳趋势，无职业和自由职业者为主要感染人群，感染者从高危人群向社会各种人群传播，呈现感染人群多样化，流行形势复杂化的特点。实施和加强防治芡滋病知识在献血活动中的宣传，进一步强化招募各环节管理，不断提高检测水平，最大限度筛除高危人群献血，确保血液安金；Objective To do blood donation analysis on detection of anti-HIV in Qinghai Xining area from 2008 to 2013 and improve blood recruitment acquisition work. To prevent the occurrence of transfusion transmitted HIV. To ensure the safety of clinical blood transfusion. Methods Anti-HIV was detected by ELISA method,screening positive hy Western Blot （WB） for confirmation, statistics and analysis of the test results. Results A total of 201 652 blood donors were detected,WB confirmed 54 cases of people infected with HIV,The positive rate was 0. 027 %. Infections in the male dominated, accounted for 90.7%, 21-〈41 years of age was the high age,accounted for 68.5%0. ELISA test,the S/CO value and the confirmatory test positive coincidence rate is proportional. A single ELISA reagent and two ELISA reagents proved the positive coincidence rate was 0% and 87 %, 54 cases of infection were the anti-HIV 1 ,specific anti HIV with gp160,gp120,P24,P17 were 100%. Conclusion A low prevalence steady trend overall HIV infection in blood donors, no freedom of occupation and occupation as the main infection, spread of infection from high-risk groups to the various social groups. Presents the infected population diversity and the popular trend of complicated characteristics. To implement and strengthen the knowledge of AIDS prevention and control in blood donation activities in the propaganda. To further strengthen the recruitment of various link management and increasing the level of detection. The maximum screen for high-risk donors to ensure the safety of blood.

关 键 词：人类免疫缺陷病毒 无偿献血者 西宁 

分 类 号：R512.91[医药卫生—内科学]