2种血糖仪检测方法与生化仪血糖检测的比对  

Evaluation of 2 methods for comparing the glucose measurement between glucose meter and automatic analyzer

作　　者：王娈[1] 胡春楠[2] 初开秋[3] 耿超[1] 

机构地区：[1]青岛大学附属医院内分泌实验室,山东青岛266003 [2]青岛大学附属医院医学美容科,山东青岛266003 [3]青岛大学附属医院检验科,山东青岛266003

出　　处：《国际检验医学杂志》2014年第18期2516-2518,共3页International Journal of Laboratory Medicine

摘　　要：目的对2种血糖仪检测方法与生化仪血糖检测进行比对,对结果、临床可操作性及影响因素进行评估。方法选取糖尿病和非糖尿病患者共61例,早晨抽取空腹静脉血2mL置于含有EDTA-K2的抗凝管中颠倒混匀。取1滴静脉血用血糖仪测静脉全血血糖(VBG),剩余标本离心取血浆用生化仪(日立7600)检测静脉血浆葡萄糖浓度(VPG)。抽取静脉血后5min内用同一血糖仪检测指尖毛细血管血糖(CBG)。以VPG为参考标准,分别计算血糖仪VBG和CBG的偏差;用统计软件分别进行VBG或CBG与VPG的相关性分析;针对VBG和CBG绘制Parkes误差网格图,判断数据的临床接受程度。结果使用罗氏公司的Accu-Chek Performa血糖仪检测静脉血糖或毛细血管血糖与生化方法血糖比对,结果呈线性相关(r分别为0.991和0.989),偏差范围均能达到国家标准,所有数据在临床可接受区。结论便携式血糖仪检测静脉血糖与生化血糖结果比对,因标本来源一致、操作流程简单、可人为制造过高或过低血糖样本,故建议医疗机构采用该方案进行定期比对实验。Objective To compare the evaluation effect ,clinical feasibility and influencing factors of two methods on comparative analyzing the blood glucose measurement of glucose meter and automatic analyzer .Methods 61 diabetic or non-diabetic patients were recruited in this study .All subjects were drawn 2 mL fasting venous blood using EDTA-K2 tubes following an 8~12 h over-night fast .One drop of venous whole blood was used to measure the blood glucose concentration （VBG）with the meter and the rest of blood was centrifuged for detecting the plasma glucose （VPG）by automatic analyzer （HITACHI-7600） .The capillary blood was taken by finger stick to test blood glucose（CBG）using the same meter within 5 min after the venous blood collection .Taking the VPG as the reference ,to calculate the respective bias of VBG and CBG .Correlation of VPG with VBG or CBG was analyzed .The clinical acceptance of glucose meter readings was evaluated by Parkes error grid analysis .Results Both VBG and CBG measured by Accu-Chek Performa glucose meter were highly correlated with VPG ,with correlation coefficient 0 .991 and 0 .989 respectively .All the measurements satisfactorily met the GB/T 19634-2005 criteria and all the results were clinically accepted .Conclusion To com-pare the results of blood glucose measured by glucose meter and automatic analyzer ,venous blood sample is recommended because of the same blood resource ,convenience of operation and possibility of making blood samples with extremely low or high glucose concentration .

关 键 词：床旁检验 血糖仪 血糖 比对分析 

分 类 号：R446.1[医药卫生—诊断学]