生物标示用3H-吲哚菁染料  

3H-Indocarbocyanine Dyes for Bioanalysis

作　　者：彭孝军[1] 王丽秋[2] 

机构地区：[1]大连理工大学精细化工国家重点实验室,大连116012 [2]齐齐哈尔大学

出　　处：《染料工业》2002年第4期8-10,12,共4页Dyestuff Industry

摘　　要：随着生物技术和荧光标示技术的飞速发展,3H-吲哚菁染料已成为在DNA、蛋白质及核酸等分析检测中使用的主要荧光探针。其中代表性化合物Cy3.、Cy5.作为新一代商品化荧光标示剂在生物芯片、分子信标等方面得到了重要应用。本文综述了该类碳菁染料在生物领域中取得的重大应用进展、并探讨了其结构与性能之间的关系。With the development of biotechnology and fluorescence labeling technology, polymethine 3H-indocarbocyanine dyes have been found to be the major fluorescent probes in bioanalysis. Cy3 and Cy5, as a new generation of the fluorescent label compounds could be used in biological chips and molecular beacons. A review of their applications in bio-analysis is presented and the property relationships between the molecular structures discussed.

关 键 词：生物标示 3H-吲哚菁染料 生物分析 吲哚碳菁染料 荧光探针 

分 类 号：TQ615[化学工程—精细化工]