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出 处:《中国实用医刊》2014年第21期61-62,共2页Chinese Journal of Practical Medicine
摘 要:目的 探讨地佐辛超前镇痛应用于膀胱镜前列腺电切术患者的有效性和安全性.方法 膀胱镜前列腺电切术患者60例,随机分为Ⅰ组和Ⅱ组,每组30例,腰硬联合麻醉下完成手术.手术操作前15 min Ⅰ组静脉注射地佐辛0.1 mg/kg,于同一时点Ⅱ组静脉注射生理盐水1ml.VAS和Ramsay评分评估两组术后2,6,12,24h的镇痛和镇静程度,比较两组手术不良反应发生情况.结果 Ⅰ组术后VAS评分低于Ⅱ组(P<0.05),两组Ram-say评分比较差异无统计学意义(P>0.05),两组间恶心呕吐、皮肤瘙瘁等不良反应发生率相比较差异无统计学意义(P>0.05).结论 膀胱镜前列腺电切术手术前应用地佐辛具有超前镇痛作用,且无明显不良反应。Objective To investigate the efficacy and safety of dezocine preemptive analgesia on cystoscopic transurethral resection.Methods Sixty cystoscopic transurethral resection of the prostate patients in combined spinal-epidural anesthesia were randomly divided into group Ⅰ and group Ⅱ,with 30 cases in each group.Group Ⅰ intravenous injection of Dezocine 0.1 mg/kg 15 min before the operation,Group Ⅱ at the same time intravenous injection saline 1 ml.The postoperative analgesia and sedation were compared using VAS and Ramsay evaluation at the time of 2,6,12,24 h after operation,the incidence of adverse reactions were compared between the two groups.Results Postoperative VAS score of group Ⅰ was significantly lower than that of group Ⅱ (P < 0.05),ramsay scores had no significant difference between the two groups(P >0.05),There were no significant difference in nausea and vomiting,skin itching and the incidence of adverse reactions between the two groups (P > 0.05).Conclusions Dezocine preemptive used in cystoscopic transurethral resectionc before operation has the preemptive analgesia effect,and no adverse reaction.
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