急性冠脉综合征患者颈动脉斑块和NT-ProBNP的相关关系探讨  

The relationship between carotid artery plaque and NT-ProBNP in acute coronary syndrome

作　　者：方石虎[1] 毛蓓[2] 李起栋[1] 廖凯[1] 周继光[1] 

机构地区：[1]解放军第171医院心血管内科,江西九江332000 [2]解放军第171医院检验科,江西九江332000

出　　处：《转化医学电子杂志》2014年第5期93-94,96,共3页E-Journal of Translational Medicine

基　　金：南京军区医药卫生科研基金（10MA059）

摘　　要：目的：急性冠脉综合征（ACS）患者联合检测颈动脉斑块和氨基末端脑钠肽前体（NT-ProBNP）检测的意义．方法：检测65例ACS患者和25例稳定型心绞痛（AP）患者的颈动脉斑块积分和外周静脉血中NT-ProBNP的水平．结果：①ACS患者和AP患者之间的颈动脉斑块积分和NT-ProBNP的水平均有明显的统计学差异（P＜0．05）；②ACS 患者的斑块积分和NT-ProBNP的水平呈相关关系（r ＝0．319，P ＜0．05）．结论：联合检测颈动脉斑块和NT-ProBNP对急性冠脉综合征有较好的预测价值．AIM：To evaluate the significance of combining detection of carotid artery plaque and N-terminal pro-brain natriuretic peptide （NT-ProBNP）in patients with acute coronary syndrome （ACS ）. METHODS：NT-ProBNP and carotid artery plaque score were measured in 65 patients with acute coronary syndrome （ACS）and 25 patients with stable angina pectoris （AP）.RE-SULTS：（1 ）The levels of NT-ProBNP and carotid artery plaque score were significant difference between patients with ACS and AP （P〈0.05）;（2）There were significant relationship between the level of NT-ProBNP and carotid artery plaque score in patients with ACS （r=0.31 9,P〈0.05 ）.CONCLUSION：Combined detection of carotid artery plaque and NT-ProBNP was a better predictive value for acute coronary syndrome.

关 键 词：急性冠脉综合征 冠心病 颈动脉斑块 氨基末端脑 

分 类 号：R541.1[医药卫生—心血管疾病]