脑梗死患者的血清同型半胱氨酸水平及其颈动脉硬化关系的临床观察  

Clinical observation of the relation between serum homocysteine levels and a carotid artery atherosclerosis

作　　者：杨运周[1,2] 方波[1,2] 胡文霞[1,2] 

机构地区：[1]安徽医科大学附属六安医院神经内科 2 病区,安徽六安237005 [2]安徽省六安市人民医院神经内科 2 病区,安徽六安237005

出　　处：《中国卫生产业》2014年第23期18-19,共2页China Health Industry

摘　　要：目的探讨血清同型半胱氨酸水平与颈动脉硬化的关系。方法选取64例脑梗死患者,检测血清同型半胱氨酸水平,将其分为高同型半胱氨酸血症组和对照组,行颈动脉超声检查,比较两组颈动脉粥样硬化与血同型半胱氨酸之间关系。结果高同型半胱氨酸血症组与对照组比较,内中膜厚度(左侧1.14±0.38vs 0.84±0.17,右侧1.19±0.29 vs 0.89±0.25),斑块的形成(64.7%vs34.7%)及狭窄的概率(70.6%vs33.3%)有显著差异(P<0.05),高同型半胱氨酸血症组有动脉斑块患者明显高于观察组,差异有统计学意义(P均<0.05)。结论高同型半胱氨酸可导致动脉硬化。Objective To study the relation between serum homocysteine levels and carotid artery atherosclerosis. Methods We selected the 64 cases of cerebral infarction. The patients were divided into hyperhomocysteine group and the control group according to their serum homocysteine levels. By detecting carotid artery ultrasonography,We compared two groups of relationship between carotid artery atherosclerosis and serum homocysteine levels. Results There was a significant difference in carotid artery therosclerosis between hyperhomocysteine group and the control group（P〈0.05）,intima-media thickness（left side：1.14±0.38 vs 0.84±0.17,right side ：1.19±0.29 vs 0.89±0.25）, plaque formation（64.7%vs34.7%） and narrow probability（70.6%vs33.3%）. Conclusion Hyperhomocysteine can lead to carotid artery atherosclerosis.

关 键 词：血清同型半胱氨酸 超声检查 动脉粥样硬化 

分 类 号：R725[医药卫生—儿科]