D-二聚体在急性胰腺炎临床分型及严重程度评估中的意义  

Significance of D-dimer in clinical classification and severity of acute pancreatitis

作　　者：崔婷婷[1] 张莉[1] 高杨[1] 吴琦玮[1] 陆玓[1] 

机构地区：[1]首都医科大学石景山教学医院北京市石景山医院消化内科,北京100043

出　　处：《中国当代医药》2014年第30期82-84,共3页China Modern Medicine

摘　　要：目的探讨D-二聚体在急性胰腺炎(AP)临床分型及严重程度评估中的意义。方法选取45例AP患者,将其分为轻度AP(MAP)组22例,中度AP(MSAP)组19例,重度AP(SAP)组4例,入院即刻抽取其静脉血,应用全自动血凝仪,采用免疫比浊法测定D-二聚体含量。入院24 h内完善胰腺增强CT检查,计算MCTSI评分。结果MAP、MSAP、SAP组的D-二聚体含量分别为(588.95±644.44)、(2170.53±3035.69)、(5362.50±2884.26)μg/L;散点图提示D-二聚体含量与MCTSI呈正相关,Spearman秩相关提示两者呈正相关(r=0.593,P<0.01)。结论 D-二聚体与AP严重程度呈正相关,可作为早期判断AP严重程度的指标之一。Objective To discuss the significance of D-dimer in clinical classification and severity of acute pancreatitis （AP）. Methods 45 patients with AP were selected and divided into the mild acute pancreatitis （MAP） group （n=22）,the moderately severe acute pancreatitis （MSAP） group （n=19） and the severe acute pancreatitis （SAP） group （n=4）.0n ad-mission,patients were given the venous blood extraction,full automatic blood coagulation analyzer and immunotur-bidimetry were used to the content of D-dimer.Pancreatic enhancement CT examination was improved into the hospital within 24 hours to count the MCTSI score. Results The content of D-dimer of the MAP, MSAP and MAP group was （588.95±644.44）, （2170.53±3035.69）, （5362.50±2884.26） μg/L respectively;scatterplot suggested that the content of D-dimer was positively associated with MCTSI,Spearman rank correlation suggested that there was a positive correlation between them （r=0.593,P〈0.01）. Conclusion There was positive correlation between the content of D-dimer and the severity of acute pancreatitis.It could be used as one of the indexes of judging the severity of acute pancreatitis in the early stage.

关 键 词：急性胰腺炎 D-二聚体 MCTSI评分 分型 

分 类 号：R657.51[医药卫生—外科学]