乌鲁木齐市维汉儿童乙肝抗体滴度水平调查  

Investigation of the titer level of hepatitis B antibody in Uygur and Han children in Urumqi

作　　者：王培生[1] 芮宝玲[1] 陈保林[1] 罗新[1] 

机构地区：[1]乌鲁木齐市疾病预防控制中心,新疆乌鲁木齐830026

出　　处：《现代预防医学》2014年第20期3703-3704,3714,共3页Modern Preventive Medicine

摘　　要：目的了解乌鲁木齐市维族与汉族儿童乙肝抗体滴度水平,为指导该市乙肝防控提供理论依据。方法通过随机整群抽样的方式选择1~7岁儿童350例,其中汉族255例,维族95例,使用ELISA法检测乙肝表面抗体含量。结果不同民族、不同年龄分组儿童的乙肝表面抗体阳性率差异有统计学意义（P〈0.05）;不同民族之间乙肝表面抗体滴度差异有统计学意义（P〈0.05）,不同年龄分组、不同性别之间乙肝表面抗体滴度值差异无统计学意义（P〉0.05）。结论应加强少数民族、高年龄儿童乙肝疫苗免疫工作,以提高其对乙肝的保护效用。Objective The objective of the study was to assess the titer level of hepatitis B antibody in Uygur and Han children in Urumqi, so to provide a reference for the prevention and control of hepatitis B in Urumqi. Methods 350 children aged between 1 and 7, including 255 Han and 95 Uygur children, were selected by random cluster sampling. ELISA was used to determine the content of hepatitis B surface antibodies. Results Positive rate of hepatitis B surface antibody varied among children of different ethnics and in different age groups （P〈0.05）, and titer level of hepatitis B surface antibodies differed between ethnics （P〈0.05）. No significant difference in hepatitis B surface antibody titer was observed between different age groups and gender （P〉0.05）. Conclusion Immunization with hepatitis B vaccine for ethnic minorities and older children should be strengthened to improve its protective effect against hepatitis B.

关 键 词：乙肝抗体 影响因素 维吾尔族 汉族 

分 类 号：R179[医药卫生—妇幼卫生保健]