江西省2010-2013年乙型肝炎疫苗接种后疑似预防接种异常反应现状分析  

Current status analysis of adverse events following hepatitis B immunization in Jiangxi Province between 2010 and 2013

作　　者：郭世成[1] 谭楚生[1] 郑敏[1] 程慧健[1] 

机构地区：[1]江西省疾病预防控制中心,江西南昌330029

出　　处：《现代预防医学》2014年第20期3784-3785,共2页Modern Preventive Medicine

摘　　要：目的了解江西省使用的乙型肝炎疫苗的安全性。方法分析江西省2010-2013年通过全国疑似预防接种异常反应信息管理系统收集到的与接种乙型肝炎疫苗有关的AEFI数据。结果江西省2010-2013年共报告与接种乙型肝炎疫苗有关的AEFI病例462例,报告发生率为5.39/10万,其中异常反应67例,报告发生率为0.78/10万。异常反应病例中过敏性皮疹最多,有39例,报告发生率为4.55/100万。结论江西省使用的乙型肝炎疫苗不良反应报告发生率未超过全国平均水平,具有较好的安全性。Objective The study aimed to assess the safety of hepatitis B vaccine used in Jiangxi Province. Methods Data on adverse events following immunization （AEFI） with hepatitis B vaccine obtained by the National AEFI Information Management System in Jiangxi Province between 2010 and 2013 were analyzed. Results A total of 462 AEFI cases related to hepatitis B vaccine were reported in Jiangxi Province between 2010 and 2013, with an incidence of 5.39/100 000; the cases included 67 cases of adverse reactions, with an incidence of 0.78/100 000. Allergic eruption was among the most common adverse reactions, with 39 cases reported and an incidence of 4.55/1 000 000. Conclusion The reported incidence of adverse events following hepatitis B vaccination in Jiangxi Province is lower than the national average, confirming the safety of the vaccine.

关 键 词：乙型肝炎疫苗 疑似预防接种异常反应 分析 

分 类 号：R186[医药卫生—流行病学]