我院2013年7～12月糖皮质激素类药物使用分析  

Analysis of the utilization of glucocorticoid drugs in our hospital from July to December 2013

作　　者：卢协勤[1] 王萍[1] 蔡惠惠[1] 姚祯[2] 

机构地区：[1]南京医科大学第二附属医院,江苏南京210011 [2]南京医科大学药学院,江苏南京210029

出　　处：《中国医药导报》2014年第30期92-97,128,共7页China Medical Herald

摘　　要：目的调查统计南京医科大学第二附属医院（以下简称＂我院＂）糖皮质激素类药物的使用情况,并对使用的合理性进行评价分析,为临床合理用药提供参考。方法统计用药频度（DDDs）、销售金额等指标,并随机抽取我院2013年7~12月使用糖皮质激素的门诊处方772张、住院病历100份,对糖皮质激素类药物的用药数量、用药品种、处方分布、用途分布及用药合理性进行统计分析。结果 2013年7~12月糖皮质激素类药物销售金额排名前3位的是注射用甲泼尼龙琥珀酸钠（米乐松）、氢化泼尼松注射液（赣鹰）和注射用甲泼尼龙琥珀酸钠（甲强龙,500 mg）,分别为257 790、149 968和31 465元;DDDs排名前3位的是地塞米松磷酸钠注射液、醋酸泼尼松片、注射用甲泼尼龙琥珀酸钠（米乐松）,分别为117 438.7、51 219.0和19 830.0。门急诊科室使用处方数最高的前4名是儿科、皮肤科、内科、耳鼻喉科,分别为341、113、78、69张;病区使用例数最多的前4名是肿瘤科、普外科、耳鼻喉科、呼吸科,分别为11、10、8、7例。糖皮质激素类药物主要用于呼吸系统疾病、术后预防反应性炎症、过敏性疾病、皮炎、退热降低体温等。糖皮质激素类药物临床使用情况基本合理,极少数处方和病例存在不合理应用的现象,包括适应证不适宜、用法用量不合理、单纯以退热为目的使用糖皮质激素等。结论我院糖皮质激素类用药结构及治疗疾病均较合理,但还需进一步加强管理,从根源上防止滥用、乱用的现象出现,维持医疗质量安全。Objective To investigate the utilization of glucocorticoid drugs in The Second Affiliated Hospital of Nanjing Medical University（ ＂our hospital＂ for short）, and analyze the rationalisation of use, to provide reference for rational drug use of glucocorticoid in clinic. Methods DDDs and consumption sum were analyzed. 772 outpatient prescriptions and 100 medical records of glucocorticoid drugs in our hospital were selected randomly from July to December 2013.The drug amount, variety, distribution of prescription, utilization and rationality were analyzed. Results Methylprednisolone Sodium Succinate Powder-injection（Mi Le Song）, Hydroprednisone Injection（Gan Ying） and Methylprednisolone Sodium Succinate Powder-injection（Jia Qiang Long, 500 mg） were ranked as the top three in the consumption sum of glucocorticoid, it were respectively 257 790, 149 968 and 31 465 yuan dynasty. Dexamethasone Sodium Phosphate Injection, Prednisolone Acetate Piece and Methylprednisolone Sodium Succinate Powder-injection（Mi Le Song）were ranked as the top three in the DDDs of glucocorticoid, it were respectively 117 438.7, 51 219.0 and 19 830.0from July to December 2013. The Paediatrics Department, Dermatology Department, Internal Medicine and Ear-nosethroat Department were the top four of the prescription number in outpatient, it were respectively 341, 113, 78 and 69 stretch. The Oncology Department, General Surgery Department, Ear-nose-throat Department and Pneumology Department were the top four of case load in ward, it were respectively 11, 10, 8 and 7 cases. The glucocorticoid drugs were mainly used for disease of respiratory system, precaution inflammatory reaction in postoperation, anaphylactic disease,dermatitis and bring down a fever. The utilization of glucocorticoid drugs was basic rational in our hospital. But there were unreasonable prescriptions and cases in tiny minority including indication inaptitude, use and dosage unreasonable, alone bring down a fever, et al. Conclusion The construction of glucoco

关 键 词：糖皮质激素类药物 销售金额 用药频度 使用分析 

分 类 号：R969.3[医药卫生—药理学]