小儿轮状病毒肠炎的肾损害的临床分析  

The Clinical Analysis on Renal Damage of Infantile Rotavirus Enteritis

作　　者：李建安[1] 鄢能荣 吴建武[1] 

机构地区：[1]广东省深圳市宝安区石岩人民医院,广东深圳518108

出　　处：《中国医学创新》2014年第29期146-148,共3页Medical Innovation of China

摘　　要：目的:探讨血清CysC在轮状病毒肠炎患儿肾损害中的诊断价值及患儿肾损害的情况。方法:对131例确诊为轮状病毒感染的腹泻患儿(观察组)和94例正常婴幼儿(对照组)进行血清CysC的检测,同时进行血清BUN和Cr的测定。结果:观察组血清CysC阳性共36例,阳性率为27.48%;对照组全部阴性,两组血清CysC异常的发生率比较差异有统计学意义(P<0.05)。血清CysC异常程度与脱水程度无关,与患儿年龄有关,年龄越小越易发生CysC异常。结论:轮状病毒性肠炎可造成肾脏损害,引起血清CysC升高。Objective：To investigate the diagnostic value of serum Cystatin C in renal damage of the children with rotavirus enteritis and the damage to kidney of the children.Method：Serum Cystatin C detection was carried out among 131 children（observation group）diagnosed definitely as rotavirus enteritis and 94 normal infants（control group）, meanwhile,serum urea nitrogen and creatinine levels were detected.Result：In observation group,36 children were found with positive serum Cystatin C,the positive rate was 27.48%.In control group,all the 94 children were negative, there was significant difference in the positive rate of serum Cystatin C between the two groups（P〈0.05）.The degree of serum Cystatin C abnormality was not related to the degree of dehydration of children,the incidence of abnormal serum Cystatin C was related to the age of children,the smaller the children were,the easier they had abnormal serum Cystatin C.Conclusion：Rotavirus enteritis may induce kidney damage and the increase of serum Cystatin C.

关 键 词：轮状病毒 肾脏 

分 类 号：R725.1[医药卫生—儿科]