65746例患者手术前梅毒抗体检测结果分析  

Analysis on results of syphilis antibody testing for 65746 patients before operation

作　　者：杨华[1] 卢建明[1] 杨晓东[1] 饶丽华[1] 

机构地区：[1]三峡大学仁和医院检验科,湖北宜昌443001

出　　处：《现代预防医学》2014年第21期3970-3972,共3页Modern Preventive Medicine

摘　　要：目的探讨住院手术患者手术前梅毒抗体的流行病学特征,为医院制定感染控制预防措施提供科学依据。方法用化学发光微粒法对2009-2013年65 746例住院手术患者进行梅毒抗体初筛,阳性标本用TPPA确诊。结果在65 746份血液标本中,共初筛出梅毒抗体阳性2 050例,经TPPA确诊阳性1 874例,梅毒抗体阳性率为2.85%,其中外科33 850份血液标本,检出梅毒阳性1 115例,梅毒阳性率最高,为3.29%,其次为妇产科、内科385和374例,阳性率分别为2.88%和2.02%;经统计学分析,不同科室间的阳性率差异有统计学意义（P〈0.05）;男性32 654份标本,检出梅毒抗体阳性1 023例,女性33 092份标本,检出梅毒抗体阳性851例,男、女阳性率分别为3.13%、2.57%,不同性别间的阳性率差异有统计学意义（P〈0.05）;感染者年龄段中梅毒阳性率最高的是41~50岁,在18 427份血液标本中,检出梅毒抗体阳性746例,阳性率为4.05%;梅毒抗体阳性患者中,潜伏期梅毒患者1538例,占阳性患者总例数的82.07%。结论梅毒抗体阳性患者每年呈逐渐上升趋势,对住院患者进行梅毒抗体检测分析,可及早控制感染源,建立以切断传播途径为主的预防控制措施。Objective To analyze the epidemiological characteristics of syphilis antibody in hospital, to provide scientific bases for prevention and control strategies. Methods The 65 746 patients come from 2009-2013 years were syphilis antibody screened by chemiluminescence immune assay, positive TPPA and then confirmed. Results By detecting TPPA, in 65 746 cases of specimens, there were 1 874 positive cases, the positive rate of syphilis antibody was 2.85%, of 33 850 blood specimens in department of surgery, the syphilis antibody was tested positive in 1 115 cases, the positive rate of the syphilis antibody was the highest （3.29%）, followed by the obstetrics and gynecology department （385 cases, 2.88%）, outpatient department （374 cases, 2.02%）, the statistical analysis showed that the difference in the positive rate between the various departments was statistically significant （P〈0.05）; of 32 654 male cases of specimens, there were 1 023 cases with syphilis antibody tested positive; of 33 092 female cases of specimens, there were 851 cases with syphilis antibody tested positive; the positive rates of the male and female were 3.13% and 2.57%, respectively, and the difference in the positive rate between the genders was statistically significant; the positive rate of the syphilis antibody was the highest in the patients aged between 41 and 50 years old; of 18 427 blood samples, there were 746 cases with the syphilis antibody tested positive, the positive rate was 4.05%; the patients with positive syphilis antibody, there were 1 538 cases in incubation period of syphilis, the rate was 82.07%. Conclusion Every year, the patients with positive syphilis antibody show a rising trend. The analysis for hospitalized patients with syphilis antibody could control the infection sources in the early stage, establish prevention and control measures to cut off the main route of transmission.

关 键 词：梅毒抗体 结果 分析 

分 类 号：R115[医药卫生—公共卫生与预防医学]