不同血液净化方式对维持性血液透析患者甲状旁腺素的影响  

The Effect of Different Blood Purification Methods on the Parathyroid Hormone of Patients with Maintenance Hemodialysis

作　　者：余娜[1] 

机构地区：[1]焦作市人民医院肾内科,河南焦作454002

出　　处：《中外医疗》2014年第25期36-37,共2页China & Foreign Medical Treatment

摘　　要：目的探讨不同血液净化方式对维持性血液透析患者甲状旁腺素(PTH)的影响。方法将该院维持性血液透析患者62例随机分成3组:即血液透析组(HD)10例,血液透析+血液灌流组(HD+HP)27例,血液透析+血液透析滤过组(HD+HDF)25例。各组均于治疗前及治疗12周后检测PTH水平。结果 HD组治疗前后PTH水平差异无统计学意义(P=0.089,P>0.05);HD+HP组及HD+HDF组治疗前后PTH水平均有不同程度下降(P=0.002,P=0.005,均为P<0.01),且HD+HP组比HD+HDF组PTH水平下降更为显著,差异有统计学意义(P=0.012,P<0.05)。结论 HD+HP及HD+HDF血液净化方式能有效降低维持性血液透析患者PTH水平,且HD+HP方式优于HD+HDF。Objective To explore the effect of different blood purification methods on the parathyroid hormone （PTH） of patients with maintenance hemodialysis. Methods 62 patients underwent maintenance hemodialysis in our hospital were randomly divided into 3 groups： hemodialysis（HD） group（n=lO）, hemodialysis ＋hemoperfusion（HD＋HP） group（n=27）, hemodialysis＋hemodiafihration （HD＋HDF） group （n=25）. The levels of PTH of the three groups of patients were detected before treatment and 12 weeks after treatment. Results There were no significant changes of PTH levels before and after treatment in group HD（P=-0.089, P〉0.05）. PTH levels decreased before and after treatment with different degrees in group HD＋HP and HD＋HDF （P=-0.002; P=0.005, all P〈0.01）, and PTH levels decreased more significantly in group HD＋HP than in group HD＋HDF（P=0.012, P〈0.05）. Conclusion HD＋HP and HD＋HDF blood purification methods can effectively reduce the PTH. level of maintenance hemodialysis patients, and HD＋HP is better than HD＋HDF.

关 键 词：甲状旁腺素 血液透析 血液灌流 血液透析滤过 

分 类 号：R4[医药卫生—临床医学]