人群聚集场所人员结核分枝杆菌潜伏感染状况分析  

The analysis of latent mycobacterium tuberculosis infection in congregate population

作　　者：刘倩倩[1] 石亚萍[1] 栗方芝 李娜娜[1] 马苗苗[1] 陈玲[1] 

机构地区：[1]遵义医学院附属医院呼吸二科、呼吸医学研究室,遵义贵州563003

出　　处：《世界最新医学信息文摘》2014年第28期51-51,53,共2页World Latest Medicine Information Electronic Version

基　　金：1.国家“十二五”科技重大专项“结核分枝杆菌潜伏感染新型生物标志候选物的筛选”2013ZX10003007-001-003。2.贵州省结核病综合防治2011协同创新中心(培育)项目

摘　　要：目的：了解人群聚集场所人员结核分枝杆菌潜伏感染状况。方法使用结核感染t细胞检测试剂盒（TB-IGRA）,对人群聚集场所人员组（92例）、活动性肺结核组（78例）及医疗卫生人员组（23例）分别进行TB-IGRA试验,了解各组结核分枝杆菌潜伏感染情况。结果193例受检人员中,128例IGRA试验阳性,总阳性率66.3%。人群聚集场所人员IGRA试验阳性率为65.2%（60/92）；活动性肺结核组IGRA试验阳性率79.5%（62/78）；医疗卫生人员IGRA试验阳性率26.1%（6/23）。结论人群聚集场所人员结核潜伏感染率高，应加强相关防护措施。Objective to study the latent tuberculosis infection （ltBi） in congregate population. Methods a total of 193 cases, including 92 people in a congregate place, 78 patients with active pulmonary tuberculosis and 23 health care workers, were collected respectively to detect Mycobacterium tuberculosis infection through gamma interferon release assay （TB-IGRA）. Results 128 cases’ TB-IGRA results were positive and the positive rate was 66.3%. the TB-IGRA positive rate in the congregate workers was 65.2%（60/92）, the positive rate of patients with active pulmonary tuberculosis and the health care workers was 79.5%（62/78） and 26.1%（6/23）, respectively.Conclusion there is high latent tuberculosis infection rate in congregate people, therefore, essential protective measures should be applied.

关 键 词：结核分枝杆菌 潜伏感染 TB.IGRA 人群聚集场所人员 

分 类 号：R19[医药卫生—卫生事业管理]