不同大小泽泻23-乙酰泽泻醇B含量及红外指纹图谱比较  

Comparison on Contents of 23-Acetate Alisol B and Infrared Spectrometry Fingerprint Among Rhizoma Alismatis of Different Specifications

作　　者：张亚敏 林文津 徐榕青 宋晓瑞 汤权森 

机构地区：[1]福建省医学科学研究院福建省医学测试重点实验室,福建福州350001

出　　处：《中国中医药信息杂志》2014年第11期92-94,共3页Chinese Journal of Information on Traditional Chinese Medicine

基　　金：国家自然科学基金(81102875);福建省科技计划项目(2013R0034-3)

摘　　要：目的比较不同大小泽泻化学成分的差异。方法选取8种不同质量梯度的泽泻药材,采用高效液相色谱法测定其23-乙酰泽泻醇B含量,应用傅里叶变换红外光谱法测定其指纹图谱。结果 8种不同质量梯度泽泻中23-乙酰泽泻醇B含量均在0.06%以上,并且其大小与23-乙酰泽泻醇B含量没有相关性(P>0.05),红外指纹图谱相似度均在0.9以上。结论不同大小泽泻的化学成分基本相同,其23-乙酰泽泻醇B含量符合《中华人民共和国药典》规定。Objective To compare the chemical components among Rhizoma Alismatis of different specifications. Methods Rhizoma Alismatis of 8 different weights were chosen, and then contents of 23-acetate alisol B were determined by HPLC, and infrared spectrometry fingerprint was determined by Fourier transform infrared spectroscopy. Results The contents of 23-acetate alisol B in Rhizoma Alismatis of 8 different specifications were over 0.06%, and had no relation with specification of Rhizoma Alismatis （P〉0.05）. The similarities of infrared spectrometry fingerprint were above 0.9. Conclusion The chemical components among Rhizoma Alismatis of different specifications were basically the same. Contents of 23-acetate alisol B of Rhizoma Alismatis of 8 different specifications conformed to regulation of China Pharmacopoeia.

关 键 词：泽泻 23-乙酰泽泻醇B 高效液相色谱法 红外光谱 指纹图谱 

分 类 号：R284.1[医药卫生—中药学]