低渗口服补液盐治疗小儿轮状病毒肠炎疗效观察  

Hypotonic oral rehydration salt for infantile rotavirus enteritis

作　　者：钟乐璇[1] 

机构地区：[1]广州医科大学附属第二医院儿科,广州510260

出　　处：《国际医药卫生导报》2014年第22期3451-3453,共3页International Medicine and Health Guidance News

摘　　要：目的 探讨低渗口服补液盐治疗小儿轮状病毒肠炎的临床疗效.方法 选取我院收治的128例轮状病毒肠炎患儿,随机均分为对照组（口服补液盐Ⅰ治疗）和观察组（低渗口服补液盐治疗）.比较两组患儿临床症状、体征改善情况、治疗前后血钠水平和治疗总有效率的差异.结果 观察组腹泻持续时间、脱水纠正时间、大便排出量分别为（4.1±1.3）d、（1.1±0.4）d、（47.1±3.7） ml/（kg·24 h）,均显著低于对照组（P＜0.05）;观察组治疗前、后血钠水平比较差异无统计学意义（P＞0.05）,对照组血钠水平较治疗前显著升高（P＜0.05）;观察组和对照组治疗总有效率分别为96.9％、92.2％,组间比较差异无统计学意义（JP＞0.05）.结论 低渗口服补液盐治疗小儿轮状病毒肠炎疗效确切,值得临床推广使用.Objective To investigate the clinical efficacy of hypotonic oral rehydration salt for infantile rotavirus enteritis.Methods 128 cases of infantile rotavirus enteritis admitted into our hospital were randomly divided into a control group （treated with oral rehydration salts Ⅰ） and an observation group （treated with hypotonic oral rehydration salts）.The clinical symptoms and signs,serum sodium before and after treatment,and the total effective rates of the two groups were compared.Results The duration of diarrhea,the dehydration correct time,and the quantity of defecate eduction were （4.1 ± 1.3） d,（1.1 ± 0.4） d,and （47.1 ± 3.7） ml/（kg·d） in the observation group,which were significantly lower than those in the control group （P 〈 0.05）.There was no statistical difference in serum sodium between before and after the treatment in the observation group （P 〉 0.05）.The serum sodium was significantly higher after than before the treatment in the control group （P 〈 0.05）.The total effective rate was 96.9% in the observation group and was 92.2% in the control group,with no statistical difference （P 〉 0.05）.Conclusions Hypotonic oral rehydration salt for infantile rotavirus enteritis has certain effect and is worth being clinically generalized.

关 键 词：低渗口服补液盐 口服补液盐Ⅰ 轮状病毒肠炎 

分 类 号：R725.1[医药卫生—儿科]