四氢吡咯并吲哚啉衍生物的晶体结构及抗菌活性研究  

Crystal Structure and Biological Activity of Pyrroloindoline Derivates

作　　者：刘培均[1] 刘小卒[1] 王思倚 

机构地区：[1]遵义医学院药学院,贵州遵义563000

出　　处：《广东化工》2014年第19期39-40,共2页Guangdong Chemical Industry

摘　　要：解析了吡咯并吲哚啉衍生物1的单晶结构,体外抗菌实验表明1、2对金黄色葡萄球菌具有抑菌活性,其中1的MIC为75 ug/mL,2的MIC为37.5 ug/mL。The crystal structure of pyrroloindoline derivate I was determined by single X-ray diffraction. Antibacterial activity tests of compound 1-4 indicated that compound 1 and 2 exhibited antibacterial activity against Staphylococcus aureus with 75 ug/mL MIC and 37.5 ug/mL MIC respectively.

关 键 词：四氢吡咯并吲哚啉衍生物 单晶结构 抗菌活性 合成 

分 类 号：TQ[化学工程]