慢性阻塞性肺疾病患者抑郁和焦虑症状与BODE指数关系的相关性分析  

Analysis the relation of anxiety and depression in patients with chronic obstructive pulmonary disease and the BODE index

作　　者：赵新国[1] 黄利华[1] 黄捷晖[1] 张艳[1] 储美萍[1] 白金梅[1] 

机构地区：[1]无锡市第五人民医院,214005

出　　处：《中华肺部疾病杂志（电子版）》2014年第5期34-36,共3页Chinese Journal of Lung Diseases(Electronic Edition)

基　　金：南京医科大学科技发展基金项目(2011NJMU117)

摘　　要：目的 探讨急性加重期及稳定期慢性阻塞性肺疾病（COPD）患者的抑郁和焦虑症状与患者BODE指数的相关性,指导临床工作中及时判定COPD患者是否存在抑郁和焦虑症状.方法 采取随机对照研究,选用我院2012年1月到2013年6月就诊的急性加重期及稳定期COPD患者94例,采用量表分析等方法观察其焦虑抑郁评分及BODE指数.结果 两组患者BODE指数、焦虑评分、抑郁评分及氧分压有显著性差异,两组患者Hamilton焦虑量表（HAMA）评分均大于7分,Hamilton抑郁量表（HAMD）评分均大于8分.HAMA、HAMD评分与BODE指数呈线性关系：随着BODE指数增加,HAMA评分（R2为0.575）、HAMD评分（R2为0.503）亦随之增加.BODE评分分为Ⅰ～Ⅳ级后,Ⅰ、Ⅱ级患者无焦虑,Ⅲ、Ⅳ级有焦虑存在;抑郁BODE分级各级均存在.除Ⅰ、Ⅱ级外,随着BODE分级的增高,焦虑抑郁评分越高.结论 通过临床易于操作的量表分析COPD患者情绪状态变化特点,可以指导临床医师尽早认识并处理患者的异常情绪状态,并对其焦虑抑郁程度作出正确的判定.Objective To know about the relationship of depression,anxiety and the （body mass,airflow obstruction,byspnea,xercisecapacity index） BODE indexes in chronic obstructive pulmonary disease （COPD） by investigate the depression and anxiety status quo of patients with COPD or AECOPD,and thus providing better guidance for clinical diagnosis patients with COPD whether had symptoms of depression and anxiety or not in time.Methods It was chosen that 94 patients with COPD or AECOPD in our hospital from January 2012 to June 2013,by randomized controlled study.It was observed that patients＇ anxiety and depression score and BODE index by scale analysis.Results Two groups had a marked improvement in BODE index,anxiety and depression score for their HAMA both over 7 and HAMD both over 8.HAMA and HAMD have a linear relation with BODE index：as BODE index increased,the HAMA （R2 was 0.575）,the HAMD （R2 was 0.503） also increasing.When BODE scores was classified into Ⅰ-Ⅳ grades,Ⅰ,Ⅱ class patients without anxiety,but those class Ⅲ and Ⅳ have anxiety.There was depression in all levels of BODE index classification.Except class Ⅰ and Ⅱ,the anxiety depression score increased with the increase of BODE grade.Conclusions Though the clinical emotional scale,Mood changes of the patients with COPD are analyzed can guide clinical doctors know and treat patients with abnormal emotional state as soon as possible.And make a right judgment of the degree on anxiety depression patients.

关 键 词：肺疾病 慢性阻塞性 焦虑 抑郁 BODE指数 

分 类 号：R563[医药卫生—呼吸系统]