慢性肾衰竭之“毒邪”  

The pathogenic ‘toxins' of chronic renal failure

作　　者：马晓燕[1] 刘月[1] 王艳杰[1] 

机构地区：[1]辽宁中医药大学附属医院中医内科教研室,沈阳110032

出　　处：《吉林中医药》2014年第10期1038-1040,共3页Jilin Journal of Chinese Medicine

基　　金：沈阳科学技术计划项目:肾衰饮对肾纤维化大鼠TGF-β1/Smad信号通路的作用研究(F13-220-9-18)

摘　　要：依据中医基础理论,结合多年临床实践积淀,提出慢性肾衰竭,顽固缠绵,脏腑虚衰,变证丛生,是"毒邪"深伏久滞、广泛内损、兼夹依附、暴戾酷烈等特性的体现;其病机为内毒深伏,肾络受损;湿毒、瘀毒是其顽恶难愈,迁延反复之关键;从解毒、排毒、抗毒三法论治,强调"审因论治"以解毒;药浴、利尿、通腑、敷脐以排毒;健脾补肾以抗毒,尤以调理脾胃为重点,全方位、多途径祛毒外出,体现中医"治病求本"的整体观念。According to the basic theory of traditional Chinese medicine,combined with years of accumulation of clinical practice,we proposed that chronic renal failure,stubborn lingering,organs virtual failure,and concurrent complications were the reflections of the characteristics of toxins such as deep long stagnation,widespread in the loss,clip attachment and violent.Their pathogenesis was deep internal toxin,damaged kidney collateral.Damp and stasis toxins were the key to their hardness to cure and repeatedly long delay.Treatment should be based on three methods：detoxication,detoxification and antitoxic,which emphasized that ‘treatment based on the original causes＇ was used for detoxication,medicated bath,diuretic,bowel-relaxing,umbilicus were applied for detoxification,and spleen and kidney were tonified for antitoxic,which especially focused on tonifying the spleen and stomach to detoxify comprehensively and in multiple pathways,reflecting ‘searching for the primary cause of disease in treatment＇and ‘the integral concept＇in traditional Chinese medicine.

关 键 词：慢性肾衰竭 毒邪 病因病机 致病要点 辨证论治 解毒 排毒 抗毒 

分 类 号：R241.6[医药卫生—中医诊断学]