广西地区宫颈意义未明的非典型鳞状细胞患者临床病理特点研究  

The clinicopathological features of patients with cervical atypical squamous cells of undetermined significancein Guangxi district

作　　者：周祥祯[1] 卢军营[1] 申小雄 李雪[1] 韦荣干[1] 莫祥兰[1] 

机构地区：[1]广西壮族自治区人民医院病理科,南宁530021

出　　处：《中国临床新医学》2014年第10期909-911,共3页CHINESE JOURNAL OF NEW CLINICAL MEDICINE

基　　金：广西科学技术研究与开发计划项目(编号:桂科攻114003B-68)

摘　　要：目的：比较广西地区宫颈液基细胞学诊断为意义未明的非典型鳞状细胞（ ASCUS）的组织学诊断结果，寻找合理的ASCUS患者管理方法。方法复习237例有组织病理学诊断的ASCUS患者临床病理资料。结果237例患者年龄19-67岁，中位年龄41岁，48例为绝经后妇女。223例患者无临床症状。专科检查，108例宫颈光滑，105例宫颈糜烂，23例宫颈肥大。组织学诊断为宫颈黏膜慢性炎伴鳞状上皮单纯性增生及宫颈黏膜慢性炎伴腺上皮鳞化、宫颈尖锐湿疣、宫颈上皮内病变（ CIN）Ⅰ级、CINⅡ及Ⅲ级、癌分别为121例（51.05％）、31例（13.08％）、54例（22.78％）、28例（11.80％）、3例（1.30％）。结论广西地区ASCUS患者大部分无临床症状，对ASCUS患者建议做阴道镜检查，疑为CIN或肿瘤者同时取活检，及时发现高级别CIN和癌。Objective To compare the histological diagnosis results of the cervical atypical squamous cells of undetermined significance（ ASCUS） in liquid based cytology in Guangxi district, looking for a reasonable management for the ASCUS patients.Methods The clinicopathological data of 237 cases of ASCUS with histological diagnosis were studied.Results Clinically, the age of 237 patients were ranged from 19 to 67 years old, the median age was 41 years, 48 cases of them were postmenopausal women, 94%（223 cases） of the patients were asymptoms.Gynecological examination found that 46%（108 cases） of them had smooth cervix, 44%（105 cases） had cervical erosion, and 10%（23 cases） had cervical hypertrophy.The histological diagnosis showed that cervical chronic inflammation with squamous epithelial hyperplasia and cervical chronic inflammation with glandular epithelial metaplasia was found in 121cases（51.05%）, cervical condyloma in 31 cases（13.08%）, CINⅠ in 54 cases（22.78%）, CINⅡ and Ⅲin 28 cases（11.80%）, and carcinoma in 3 cases（1.30%）.Conclusion Most of the ASCUS patients in Guangxi district are asymptoms.Colposcopy examination may be offered in ASCUS patients, and biopsy should be done at the same time when high-grade CIN or tumor are suspected, in order to find high-grade cervical precancerous lesions and cancer timely.

关 键 词：液基细胞学 非典型鳞状细胞 宫颈上皮内病变 管理 

分 类 号：R44[医药卫生—诊断学]