一种可视化检测硫化氢的苯并噻唑类荧光增强型探针  

A Benzothiazole-Derived Fluorescence Enhancement Probe for Visual Detection of H_2S

作　　者：范方禄[1] 靖金球[1] 陈雪梅[1] 

机构地区：[1]湖北理工学院化学与材料工程学院,黄石435003

出　　处：《有机化学》2014年第10期2178-2183,共6页Chinese Journal of Organic Chemistry

基　　金：国家自然科学基金(No.51173060)资助项目~~

摘　　要：以叠氮基为识别基团,合成和表征了一种苯并噻唑类荧光增强型硫化氢探针(FL),并研究了它的光谱性质.实验结果表明,FL对硫化氢有较高的选择性和灵敏度,且响应快速,抗干扰能力强,细胞毒性低,它的检出限度为8.78×10-7 mol·L-1,在He La活细胞和各种水体样品中对硫化氢的检测表明FL具有潜在的应用价值.A benzothiazole-derived fluorescence enhancement probe （FL） for the detection of H2S was synthesized and char- acterized by employing azide group as the recognition unit, and its spectral properties had been researched. The results showed that FL exhibited relatively good sensitivity and selectivity to H2S as well as fast response, it also had strong anti-interference ability and low cytotoxicity, the detection limit of H2S was estimated to be 8.78 ×10^-7mol·L^-1, and the detection of H2S in living HeLa cells and various water samples indicated that it had potential application value.

关 键 词：硫化氢 荧光探针 叠氮基 可视化 

分 类 号：O657.3[理学—分析化学]