纳洛酮联合氨茶碱治疗小儿呼吸衰竭的效果及对患儿CRP的影响观察  

Efficacy of naloxone combined with aminophylline in treatment of pediatric respiratory failure and its influence on CRP

作　　者：钟志远 丁蓉芳[2] 

机构地区：[1]广东省增城市永宁街宁西社区卫生服务中心儿科,511385 [2]南方医科大学附属南方医院儿科,广州510515

出　　处：《白求恩医学杂志》2014年第5期431-432,共2页Journal of Bethune Medical Science

摘　　要：目的探讨纳洛酮联合氨茶碱治疗小儿呼吸衰竭的临床效果及对患儿CRP的影响。方法将92例呼吸衰竭患儿随机分为两组,各46例。对照组给予常规治疗,观察组在对照组基础上给予纳洛酮联合氨茶碱治疗,对比两组临床疗效及CRP水平变化。结果观察组治疗总有效率为91.3%,高于对照组的73.9%(P<0.05);治疗后,两组CRP水平均明显降低,观察组CRP水平低于对照组(P<0.01);两组均未出现严重不良反应。结论纳洛酮联合氨茶碱治疗小儿呼吸衰竭具有较好的临床效果。Objective To investigate the efficacy of naloxone combined with aminophylline in treatment of pediatric respiratory failure and its Influence on CRP. Methods Ninety-two patients with respiratory failure were randomly divided into two groups,each group 46 cases. Patients in control group were given regular treatment while those in observation group were given additional naloxone combined with aminophylline. The clinical efficacy and changes in CRP levels of the two groups were compared. Results The effective rate of the observation group was 91. 3%,higher than that of the control group（ 73. 9%）（ P〈0. 05）. After treatment,the CRP level in observation group was lower than that of control group（ P〈0. 01）. There were no serious adverse reactions in both groups. Conclusion Naloxone combined with aminophylline has a better effect on pediatric respiratory failure.

关 键 词：小儿 呼吸衰竭 纳洛酮 氨茶碱 

分 类 号：R725.6[医药卫生—儿科]