血清甘胆酸、谷丙转氨酶、总胆汁酸检测在妊娠期肝内胆汁淤积症临床诊断中的意义  被引量:15

Clinical significance of serum CG,ALT,TBA detection in intrahepatic cholestasis of pregnancy

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作  者:谢彦玲 李晓勤[2] 豆媛媛 

机构地区:[1]乌鲁木齐市妇幼保健院,新疆830000 [2]乌鲁木齐市第四人民医院,新疆830002

出  处:《中国优生与遗传杂志》2014年第10期87-87,64,共2页Chinese Journal of Birth Health & Heredity

摘  要:目的分析血清甘胆酸(CG)、谷丙转氨酶(ALT)、总胆汁酸(TBA)测定对妊娠期肝内胆汁淤积症(ICP)的诊断价值及意义。方法采用化学发光法检测血清甘胆酸浓度,采用连续监测法检测的谷丙转氨酶(ALT)的浓度、采用循环酶法检测的总胆汁酸(TBA)的浓度。结果妊娠期肝内胆汁淤积症患者的血清甘胆酸、谷丙转氨酶、总胆汁酸测定结果均明显高于正常孕妇(P<0.05)。结论血清甘胆酸、谷丙转氨酶、总胆汁酸的测定对妊娠期肝内胆汁淤积症的诊断是密切相关的,同时监测上述指标对于诊疗ICP患者,保护母婴健康具有重要意义。Objective: Analysis of serum cholyglycine (CG) , alanine transaminase (ALT) , total bile acid (TBA) on the determination of intrahepatic cholestasis of pregnancy (ICP) diagnostic value and significance. Methods: Fluorometric determination, continuous monitoring method and enzymatic cycling method to tested concentration in the serum CG, ALT and TBA. Results: Intrahepatic cholestasis of pregnancy in patients with serum CG, ALT, TBA results were significantly higher than normal pregnant women. Conclusion: The determination of serum CG, ALT, TBA on intrahepatic cholestasis of pregnancy (ICP) have an important significance, especially for protection of maternal and child health.

关 键 词:妊娠期肝内胆汁淤积症 血清甘胆酸 谷丙转氨酶 总胆汁酸 

分 类 号:R714.25[医药卫生—妇产科学]

 

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