不同光源蓝光治疗新生儿高胆红素血症的疗效比较  

Efficacy comparison of blue-light phototherapy using different light sources on neonates with hyperbilirubinemia

作　　者：裴金娟 麦智广[1,2] 

机构地区：[1]佛山市第一人民医院 [2]中山大学附属佛山医院,广东佛山528000

出　　处：《中国优生与遗传杂志》2014年第10期93-94,共2页Chinese Journal of Birth Health & Heredity

摘　　要：目的比较蓝光发光二极管（Light-emitting diodes,LEDs）及普通蓝光治疗新生儿高胆红素血症的疗效。方法将60例2013年4月-2013年7月我院高胆红素血症足月儿随机分为LEDs组及普通组,分别实施LEDs蓝光照射及普通蓝光照射。结果 LEDs组光疗24h后血清总胆红素由（254.60±7.46）μmol/L降至（178.75±6.00）μmol/L,普通组由（236.73±9.41）μmol/L降至（167.19±7.33）μmol/L,两组疗效比较,差异无统计学意义（P=0.288）;LEDs组发热与皮疹的发生率分别为6.7%,3.3%,普通组发热与皮疹的发生率分别为33.3%,26.7%,差异均有统计学意义（P〈0.05）,其余副作用（哭闹、腹泻）的发生率差异均无统计学意义（P〉0.05）。结论 LEDs蓝光治疗足月新生儿高胆红素血症疗效与普通蓝光相当,但副作用发生率低于普通蓝光。Objective： To compare the effects of LEDs blue light and common blue light on neonates with hyperbilirubinemia. Methods： 60 Full-term infants with hyperbilirubinemia were selected from April 2013 to July 2013, and divided into LEDs group and conventional group, which were treated with LEDs blue light source and blue fluorescent tubes respectively. Results： After 24 hours of treatment, the decrease in total serum bilirubin concentration were from （254.60±7.46） μmol/L to （178.75±6.00） μmol/L in the LEDs group, from （236.73±9.41） μmol/L to （167.19±7.33） μmol/L in the conventional group, respectively. There was no difference of effect between the two groups, there was no statistical difference （P=0.288） . Hyperthermia and rash were occurred in 6.7% and 3.3% of infants in the LEDs group, 33.3% and 26.7% of infants in the conventional group, respectively （P〈0.05） ; The incidence of cry and diarrhea had no statistical difference among the two groups （P〉0.05） . Conclusions. LEDs blue light is as effective as common blue light for phototherapy of full-term infants with hyperbilirubinemia, but the frequency of side effect is less than common blue light.

关 键 词：高胆红素血症 新生儿 光线疗法 LEDS 

分 类 号：R722.1[医药卫生—儿科]