Impact of invasive treatment strategy on health-related quality of life six months after non-ST-elevation acute coronary syndrome  

作　　者：Li-Xia YANG Yu-Jie ZHOU Zhi-Jian WANG Yue-Ping LI Meng CHAI 

机构地区：[1]Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, N0. 2 Anzhen Avenue, Chaoyang District, Beijing 100029, China

出　　处：《Journal of Geriatric Cardiology》2014年第3期206-211,共6页老年心脏病学杂志（英文版）

摘　　要：BackgroundFew studies have compared change in the health-related quality of life （HRQL） following treatment of non-ST-elevation acute coronary syndrome （NSTE-ACS） with either percutaneous coronary intervention （PCI） or coronary artery bypass grafting （CABG）. This study is tocompare changes in HRQL six months after hospital discharge between NSTE-ACS pa-tients who underwent either PCI or CABG.Methods HRQL was assessed using the Seattle angina questionnaire at admission and six months after discharge in 1012 consecutive patients with NSTE-ACS. To assess associations of PCI and CABG with HRQL changes, logistic regression models were constructed treating changes in the score of each dimension of the Seattle angina question-naire as dependent variables.Results Although both the PCI and CABG groups experienced angina relief and other improvements at 6-month follow-up （P〈0.001）, the CABG relative to PCI group showed more significant improvements in angina frequency （P= 0.044） and quality of life （P= 0.028）. In multivariable logistic analysis, CABG also was an independent predictor for both im-provement of angina frequency （OR： 1.62, 95%CI： 1.09-4.63,P= 0.042） and quality of life （OR： 2.04, 95%CI： 1.26-6.92,P= 0.038） relative to PCI.Conclusions In patients with NSTE-ACS, both PCI and CABG provide great improvement in disease-specific health status at six months, with that of CABG being more prominent in terms of angina frequency and quality of life.

关 键 词：Non-ST elevation acute coronary syndrome  Quality of life  Therapeutic strategy 

分 类 号：Q51[生物学—生物化学] F126[经济管理—世界经济]