淡色库蚊对3种化学杀虫剂交互抗性的实验研究  

Experimental study on cross-resistance of Culex pipiens pallens to 3 kinds of chemical pesticides

作　　者：蒋滨[1] 李士根[2] 全芯[2] 薛庆节[2] 谭文彬[2] 刘永春[2] 王新国[3] 王怀位[3] 

机构地区：[1]山东省济宁市中区人民医院,济宁272105 [2]济宁医学院病原生物学教研室 [3]山东省寄生虫病防治研究所

出　　处：《中国血吸虫病防治杂志》2014年第5期531-533,共3页Chinese Journal of Schistosomiasis Control

基　　金：教育部留学回国人员科研启动基金(20101174);山东省自然科学基金(2009ZRB14115);山东省高等学校科技计划(J10LF01);山东省医药卫生科研计划(2001CA2CEB1)

摘　　要：目的了解淡色库蚊对常用化学杀虫剂的交互抗性,为合理使用化学杀虫剂提供依据。方法采用WHO生物测定方法,检测淡色库蚊敏感品系和抗敌敌畏、抗残杀威、抗氯氰菊酯3种抗性品系IV龄幼虫分别对敌敌畏、残杀威和氯氰菊酯3种化学杀虫剂的抗性。结果淡色库蚊抗敌敌畏品系对敌敌畏、残杀威和氯氰菊酯3种化学杀虫剂的抗性系数分别为14.47、8.96和207.27,抗残杀威品系对上述3种杀虫剂的抗性系数分别为3.27、6.93和8.65,抗氯氰菊酯品系对3种杀虫剂的抗性系数分别为2.93、1.61和501.11。结论长期使用一种化学杀虫剂易产生抗性,并对其他化学杀虫剂产生不同程度的交互抗性。使用杀虫剂时应注意选择药物品种和剂量,以避免和延缓蚊虫抗药性的产生。Objective To understand the cross-resistance of Culex pipiens pallens to common pesticides,so as to provide the evidence for improving the application of chemical pesticides. Methods The IV instar larvae of DDVP-resistant,propoxurresistant and cypermethrin-resistant strains as well as the sensitive strain of Culex pipiens pallens were collected to detect the resistance to DDVP,propoxur and cypermethrin based on the WHO bioassay method. Results The resistance coefficients of DDVP-resistant strain to DDVP,propoxur and cypermethrin were 14.47,8.96 and 207.27 respectively. The resistance coefficients of propoxur-resistant strain to DDVP,propoxur and cypermethrin were 3.27,6.93 and 8.65 respectively. The resistance coefficients of cypermethrin-resistant strain to DDVP,propoxur and cypermethrin were 2.93,1.61 and 501.11 respectively. Conclusion The resistance and cross-resistance could be generated during the long-term application of a single kind of chemical pesticide,and we should pay more attention to the varieties and dosages of them.

关 键 词：淡色库蚊 化学杀虫剂 交互抗性 

分 类 号：R384.1[医药卫生—医学寄生虫学]