阿奇霉素联合红霉素治疗小儿支原体肺炎53例疗效观察  

Clinical analysis of azithromycin combined with erythromycin in the treatment of 53 cases of mycoplasma pneumoniain children

作　　者：梁莉君[1] 梁丹[1] 吕永丰[1] 

机构地区：[1]广州市中山大学孙逸仙纪念医院药学部,510000

出　　处：《临床合理用药杂志》2014年第32期15-16,共2页Chinese Journal of Clinical Rational Drug Use

摘　　要：目的探讨阿奇霉素联合红霉素治疗小儿支原体肺炎的疗效。方法选取符合条件的支原体肺炎的患儿158例,分为红霉素组、阿奇霉素组和联合治疗组,分别为55例、50例和53例,分析比较其临床疗效。结果 3组治疗方案有效率分别为70.9%、76%、92.5%,红霉素组和阿奇霉素组的临床治疗总有效率比较差异无统计学意义(P>0.05),联合治疗组与前2组比较差异有统计学意义(P<0.05)。结论红霉素和阿奇霉素两种药物联合治疗小儿支原体肺炎,具有良好的临床效果,值得临床上推广。Objective To investigantc the clinical effect of azithromycin combined with erythromycin in treatment of mycoplasma pneumonia in children. Methdos 158 children patients with mycoplasma pneumonia were randomly divided into three groups,they were respectively given erythromycin（ 55 cases）,azithromycin（ 50 cases） and azithromycin combined with Erythromycin（ 53 cases）. The clinical curative effect of 3 groups was compared. Results The effective races of 3 groups were70. 9%,76%,92. 5% respectively. There was no statistically significant difference of total effective rate between erythromycin group and azithromycin group（ P〉0. 05）,but the azithromycin combined with erythromycin group were significantly higher than another two groups,The difference was statistically significant（ P〈0. 05）. Conclusion It is good clinical effect and safety of azithromycin combined with erythromycin in treatment of mycoplasma pneumonia in children,which is worthy to be popularized.

关 键 词：支原体肺炎 红霉素 阿奇霉素 

分 类 号：R725.6[医药卫生—儿科]