同位素稀释-气相色谱-质谱法同时测定化妆品中20种多环芳烃类化合物  

Simultaneous Determination of Twenty Polycyclic Aromatic Hydrocarbons in Cosmetics by Isotope Dilution-Gas Chromatography-Mass Spectrometry

作　　者：黄永辉 谢勇 高希 蔡小明 

机构地区：[1]福建省产品质量检验研究院,福建福州350002 [2]国家加工食品质量监督检验中心,福建福州350002

出　　处：《香料香精化妆品》2014年第5期33-37,共5页Flavour Fragrance Cosmetics

基　　金：国家质检总局科技计划资助项目(编号2012QK054)

摘　　要：建立了一种同位素稀释-气相色谱-质谱法同时测定化妆品中20种多环芳烃类化合物的方法。不同类型化妆品用环己烷以不同方法进行提取,然后采用GC-MS的选择离子模式对20种目标物进行定性、定量分析。方法具有良好线性,相关系数r均大于0.992,定量限为50μg/kg。各组分平均回收率在70.5%～114.5%,相对标准偏差在1.7%～13.6%。采用此方法测定了化妆品中多环芳烃的水平,发现某些化妆品中存在萘、1-甲基萘和2-甲基萘。A method for simultaneous determination of 20 polycyclic aromatic hydrocarbons in cosmetics by isotope dilution-gas chromatography-mass spectrometry was developed. Various cosmetic samples were extracted with cyclohexane by different methods,then qualitative and quantitative analysis were carried out by GC-MS in selected ion monitoring modes. The correlation coefficients（ r） of20 polycyclic aromatic hydrocarbons were over 0. 992,the limits of quantitation for 20 polycyclic aromatic hydrocarbons were 50μg/kg. The average recoveries of 20 polycyclic aromatic hydrocarbons in cosmetics ranged from 70. 5% to 114. 5%. In addition,the relative standard deviations（ RSDs） were in the range of 1. 7%-13. 6%. The study investigated the level of polycyclic aromatic hydrocarbons in cosmetics by this method,naphthalene,1-methyl naphthalene,2-methyl naphthalene were found in some samples.

关 键 词：化妆品 多环芳烃 同位素稀释 气相色谱-质谱法 

分 类 号：O657.63[理学—分析化学] TQ658[理学—化学]