铅中毒对儿童注意力缺陷多动障碍影响研究的meta分析  

Effect of lead poisoning on attention deficit hyperactivity disorder in children: a Meta-analysis

作　　者：王艳玲[1] 高玉敏[1] 刘颖[1] 迟宝峰[1] 

机构地区：[1]内蒙古医科大学公共卫生学院,呼和浩特市010010

出　　处：《职业与健康》2014年第20期2965-2966,2969,共3页Occupation and Health

摘　　要：目的综合评价铅中毒对儿童注意力缺陷多动障碍的影响。方法采用meta分析方法,对1992—2012年关于铅中毒与儿童注意力缺陷多动障碍相关的病例对照研究的文献进行分析。结果纳入6篇病例对照研究文献,累计病例数为1 440例,对照组1 388例。结果显示,铅中毒与儿童注意力缺陷多动障碍的发生关联明显（Z=4.52,P〈0.05）,合并OR值为2.91,OR 95%CI为1.83-4.62。结论铅中毒是儿童注意力缺陷多动障碍的一个危险因素,会增加儿童患注意力缺陷多动障碍的概率。[Objective]To comprehensively evaluate the effect of lead poisoning on attention deficit hyperactivity disorder in children.[Methods]A Meta-analysis was used to analyze the case-control studies on the relationship between lead poisoning and attention deficit hyperactivity disorder in children,which the date were searched from 1992 to 2012.[Results]A total of 6 case-control studies were retrieved,including 1 440 cases in the study group and 1 388 cases in the control group. The results showed that there was a significant relationship between lead poisoning and attention deficit hyperactivity disorder in children（ Z = 4. 52,P〈0. 05）,and the pooled OR was 2. 91（ 95% CI： 1. 83-4. 62）. [Conclusion]Lead poisoning is a risk factor of attention deficit hyperactivity disorder in children,and may increase the chance of child getting the attention deficit hyperactivity disorder in.

关 键 词：铅中毒 儿童注意力缺陷障碍 META分析 

分 类 号：R135.1[医药卫生—劳动卫生]