血管性痴呆大鼠模型的治疗方法研究进展  

Therapeutic research progress in rat models of vascular dementia

作　　者：于飞[1] 孙永馨[1] 

机构地区：[1]首都医科大学宣武医院神经内科,北京100053

出　　处：《中国比较医学杂志》2014年第9期66-71,共6页Chinese Journal of Comparative Medicine

基　　金：北京市卫生系统高层次人才学科骨干项目(2013-3-092);北京市委组织部优秀人才工程(2012D005018000007)

摘　　要：血管性痴呆是引起认知障碍的常见原因,双侧颈总动脉结扎、大脑中动脉闭塞以及原发性高血压大鼠常被作为血管性痴呆模型加以研究。本文将对此类模型的药物及非药物治疗方法研究现状进行综述,从而为血管性痴呆的临床干预提供更多的科学参考建议。Vascular dementia is one of the common causes of cognitive impairment.Occlusion of bilateral common carotid arteries, middle cerebral artery occlusion, as well as induced hypertension are major methods to make rat model for vascular dementia.The present review will summarize research progress in medical and non-medical treatment of vascular dementia rat models in order to provide theoretical direction for clinical practice.

关 键 词：血管性痴呆 认知障碍 大鼠 动物模型 治疗 

分 类 号：R332[医药卫生—人体生理学]