^18F-FDG PET-CT辅助CT引导下经皮肺穿刺活检术的应用研究  

Clinical value of 18 F-FDG PET-CT in aiding CT-guided percutaneous lung biopsy

作　　者：陈瑜凤[1] 强福林[1] 夏淦林[1] 冯峰[1] 司海峰[1] 丁勇生[1] 

机构地区：[1]南通市肿瘤医院影像科,江苏南通226361

出　　处：《实用放射学杂志》2014年第10期1714-1718,共5页Journal of Practical Radiology

基　　金：南通市科技局项目（HS2011008）.

摘　　要：目的：探讨肺部肿块18 F-FDG PET-CT 辅助 CT 引导下经皮穿刺活检术的价值。方法回顾性分析 PET-CT 辅助 CT引导下肺穿刺活检资料（研究组）57例,同期随机抽取常规CT引导下肺穿刺活检资料（对照组）75例。2组资料分别按病理结果分为恶性、可疑恶性、不能诊断、炎性、良性,并与手术病理或最终临床结果对照,计算2种穿刺方法诊断恶性肿瘤的敏感度、特异度及准确率；记录2组穿刺中穿刺针进针病灶2次获取组织的比例；2组出现气胸、出血并发症的情况。采用χ2检验比较分析。结果诊断恶性肿瘤的敏感度、特异度、准确率,研究组均高于对照组,研究组分别为96.3%（52/54）、100.0%（3/3）、96.5%（55/57）,对照组分别为88.4%（61/69）、83.3%（5/6）、88.0%（66/75）,2组均无统计学意义；2组穿刺中2次进针病灶的比例有统计学差异（χ2=10.122,P=0.001）；出现气胸、出血概率均无统计学差异。结论 PET-CT辅助CT引导下肺穿刺活检术,提高了恶性肿瘤诊断的敏感度、特异度及准确性。Objective To investigate the clinical value of PET-CT in aiding CT guided percutaneous puncture biopsy for lung mas-ses.Methods The retrospective data were analyzed including 5 7 patients with lung masses who underwent CT guided percutaneous puncture biopsy combined with PET-CT （regarded as a research group）and other 75 similar patients with single CT-guided biopsy （control group）.In two groups,it was divided with malignant,suspicious malignant,can not be diagnosed,inflammatory,benign by pathological findings,and was contrasted with the surgical pathology or final clinical results.To calculate sensitivity,specificity and accuracy of diagnosis for cancer through two puncture method.Recorded complication for pneumothorax and bleeding in two groups .Be compared analysis using the 2 test.Results In study group,it was higher for the diagnosis of malignancy sensitivity, specificity,accuracy.There were 96.3% （52/54）,100.0%（3/3）and 96.5%（55/57）in research group,while those were 88.4%（61/69）,83.3% （5/6）and 88.0% （66/75）in the control group,respectively.And no statistically significant.Between research and the control group,there was a significantly statistical difference in the rate of twice punctures in one mass （χ2= 10.122,P=0.001）.Between the two groups,there was no statistically significant difference in the pneumothorax rate and the hemorrhage rate. Conclusion PET-CT in aiding CT-guided lung biopsy improves the sensitivity,specificity and accuracy of diagnosis.

关 键 词：正电子发射断层显像 肺内病变 穿刺活检 计算机体层成像 

分 类 号：R814.42[医药卫生—影像医学与核医学] R563[医药卫生—放射医学]