硫酸氢氯吡格雷片联合阿托伐他汀钙胶囊、养心氏片治疗冠心病PCI术后心绞痛39例临床疗效观察  

Clinical Observation on Therapeutic Effect of Clopidogrel Bisulfate Tablets Combined with Atorvastatin Calcium Capsules and Yangxinshi Tablets on 78 Cases of Angina Pectoris after PCI

作　　者：张春[1] 米忠友[1] 田维君[1] 

机构地区：[1]武警重庆市总队医院急诊科,重庆400061

出　　处：《世界中医药》2014年第10期1299-1301,共3页World Chinese Medicine

摘　　要：目的:观察硫酸氢氯吡格雷片联合阿托伐他汀钙胶囊、养心氏片治疗冠心病PCI术后心绞痛的疗效。方法:将78例患者随机分为治疗组和对照组,治疗组39例,用硫酸氢氯吡格雷片联合阿托伐他汀钙胶囊、养心氏片治疗;对照组用辛伐他汀片联合阿司匹林肠溶片治疗,2组治疗12周后判断疗效。治疗前后测定TC、TG、HDL-C和LDL-C水平。结果:治疗组显效率为93.31%,对照组显效率为74.36%(2组比较P<0.01);2组TG、TC、LDL-C均较治疗前明显降低(P<0.01),而HDL-C较治疗前明显升高(P<0.01)。结论:硫酸氢氯吡格雷片联合阿托伐他汀钙胶囊、养心氏片是治疗冠心病PCI术后心绞痛的有效药物组合,能有效降低心血管事件的发生率。Objective： To observe the clinical efficacy of the Clopidogrel Bisulfate tablets combined with Atorvastatin Calcium capsules and Yangxinshi tablets on angina pectoris patients after PCI. Methods： Seventy eight patients were randomly divided into the treatment group （ n = 39） and the control group （ n = 39）. Patients in the treatment group were given Clopidogrel Bisulfate tablets combined with Atorvastatin Calcium capsules and Yangxinshi tablets, and the control group applied Simvastatin tablets combined with Aspirin Entericcoated tablets. The therapeutic effects of the two groups were evaluated after 12 weeks of treatment. The relevant indicators levels were measured, such as TC, TG, HDL-C and LDL-C. Results： The effective rates of the treatment group and control group were 93.31% and 74.36% （P 〈 0.01 ）. The levels of TG and TC and LDL-C, were significantly lower after treatment in both two groups, while the level of HDL-C was significantly increased in treatment group. Conclusion： The combination therapy of Clopidogrel Bisulfate tablets, Atorvastatin Calcium capsules and Yangxinshi tablets is an available drug combination for the treatment of angina pectoris after PCI, and it can effectively reduce the incidence of cardiovascular events.

关 键 词：冠心病 PCI术后心绞痛 联合治疗 

分 类 号：R259[医药卫生—中西医结合] R541.4[医药卫生—中医内科学]